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GLI1 GLI family zinc finger 1 [ Gallus gallus (chicken) ]

Gene ID: 396045, updated on 3-Apr-2024

Summary

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Symbol
GLI1provided by CGNC
Full Name
GLI family zinc finger 1provided by CGNC
Primary source
CGNC:10848
See related
Ensembl:ENSGALG00010025727
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
GLI
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 34
Exon count:
14
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 34 NC_052565.1 (1743459..1758719)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 34 NC_052606.1 (1584553..1599889)

Chromosome 34 - NC_052565.1Genomic Context describing neighboring genes Neighboring gene inhibin beta C chain-like Neighboring gene inhibin beta E subunit Neighboring gene DnaJ heat shock protein family (Hsp40) member C14 Neighboring gene ORMDL sphingolipid biosynthesis regulator 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Hedgehog-Gli1 signaling regelates differentiation of chicken (Gallus gallus) embryonic stem cells to male germ cells. Li D, et al. Anim Reprod Sci, 2017 Jul. PMID 28483168
  2. Asymmetric expression of Gli transcription factors in Hensen's node. Granata A, et al. Gene Expr Patterns, 2005 Apr. PMID 15749082
  3. Sonic Hedgehog signaling and Gli-1 during embryonic chick myogenesis. Teixeira JD, et al. Biochem Biophys Res Commun, 2018 Dec 9. PMID 30449599
  4. Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development. Marigo V, et al. Dev Biol, 1996 Nov 25. PMID 8948590
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in smoothened signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
zinc finger protein GLI1
Names
glioma-associated oncogene homolog 1 (zinc finger protein)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001305245.3 → NP_001292174.2  zinc finger protein GLI1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000491
    Related
    ENSGALP00010038797.1, ENSGALT00010062779.1
    Conserved Domains (4) summary
    COG5189
    Location:309 → 399
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    COG5236
    Location:204 → 470
    COG5236; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
    sd00017
    Location:315 → 337
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam09606
    Location:804 → 1141
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052565.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    1743459..1758719
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025145281.3 → XP_025001049.2  zinc finger protein GLI1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZYW8
    Conserved Domains (4) summary
    COG5189
    Location:308 → 398
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    COG5236
    Location:203 → 469
    COG5236; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
    sd00017
    Location:314 → 336
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam09606
    Location:803 → 1140
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal

  2. XM_025145279.3 → XP_025001047.2  zinc finger protein GLI1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZYW8
    Conserved Domains (4) summary
    COG5189
    Location:309 → 399
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    COG5236
    Location:204 → 470
    COG5236; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
    sd00017
    Location:315 → 337
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam09606
    Location:804 → 1141
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal

  3. XM_025145280.3 → XP_025001048.2  zinc finger protein GLI1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZYW8
    Conserved Domains (4) summary
    COG5189
    Location:309 → 399
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    COG5236
    Location:204 → 470
    COG5236; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
    sd00017
    Location:315 → 337
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam09606
    Location:804 → 1141
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052606.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    1584553..1599889
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046934201.1 → XP_046790157.1  zinc finger protein GLI1 isoform X2

  2. XM_046934199.1 → XP_046790155.1  zinc finger protein GLI1 isoform X1

  3. XM_046934200.1 → XP_046790156.1  zinc finger protein GLI1 isoform X1

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P55878.1 GenPept UniProtKB/Swiss-Prot:P55878

Gene LinkOut

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