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JAG1 jagged canonical Notch ligand 1 [ Gallus gallus (chicken) ]

Gene ID: 396043, updated on 3-Apr-2024

Summary

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Symbol
JAG1provided by CGNC
Full Name
jagged canonical Notch ligand 1provided by CGNC
Primary source
CGNC:6856
See related
Ensembl:ENSGALG00010018226
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
26
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (13191920..13227987)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (13104240..13140303)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110388 Neighboring gene uncharacterized LOC107052861 Neighboring gene microRNA 1641 Neighboring gene uncharacterized LOC112532057 Neighboring gene SLX4 interacting protein Neighboring gene uncharacterized LOC124417870 Neighboring gene MKKS centrosomal shuttling protein Neighboring gene p21 (RAC1) activated kinase 5 Neighboring gene synaptosome associated protein 25

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis. Myat A, et al. Dev Biol, 1996 Mar 15. PMID 8631496
  2. Jagged 1 regulates the restriction of Sox2 expression in the developing chicken inner ear: a mechanism for sensory organ specification. Neves J, et al. Development, 2011 Feb. PMID 21266409

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Notch binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell communication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment or maintenance of epithelial cell apical/basal polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein jagged-1
Names
C-Serate-1 protein
jagged 1 (Alagille syndrome)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    13191920..13227987
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_415035.8 → XP_415035.4  protein jagged-1 isoform X1

    UniProtKB/TrEMBL
    E1BTW5, Q90819
    Related
    ENSGALP00010026180.1, ENSGALT00010044034.1
    Conserved Domains (5) summary
    smart00215
    Location:860 → 928
    VWC_out; von Willebrand factor (vWF) type C domain
    cd00054
    Location:484 → 520
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00008
    Location:745 → 775
    EGF; EGF-like domain
    pfam01414
    Location:164 → 226
    DSL; Delta serrate ligand
    pfam07657
    Location:29 → 104
    MNNL; N-terminus of Notch ligand

  2. XM_046939525.1 → XP_046795481.1  protein jagged-1 isoform X2

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    13104240..13140303
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040668033.2 → XP_040523967.1  protein jagged-1 isoform X1

    UniProtKB/TrEMBL
    E1BTW5, Q90819
    Conserved Domains (5) summary
    smart00215
    Location:860 → 928
    VWC_out; von Willebrand factor (vWF) type C domain
    cd00054
    Location:484 → 520
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00008
    Location:745 → 775
    EGF; EGF-like domain
    pfam01414
    Location:164 → 226
    DSL; Delta serrate ligand
    pfam07657
    Location:29 → 104
    MNNL; N-terminus of Notch ligand

  2. XM_046915030.1 → XP_046770986.1  protein jagged-1 isoform X2

Nucleotide Protein
Heading Accession and Version

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