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KITLG KIT ligand [ Gallus gallus (chicken) ]

Gene ID: 396028, updated on 3-Apr-2024

Summary

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Symbol
KITLGprovided by CGNC
Full Name
KIT ligandprovided by CGNC
Primary source
CGNC:8510
See related
Ensembl:ENSGALG00010011452
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
11
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (43031098..43086555, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (43373018..43428460, complement)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene C12orf29 homolog Neighboring gene centrosomal protein 290 Neighboring gene transmembrane and tetratricopeptide repeat containing 3 Neighboring gene uncharacterized LOC112533343 Neighboring gene uncharacterized LOC101751742 Neighboring gene dual specificity phosphatase 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression and regulation of Kit ligand in the ovary of the hen. Kundu MC, et al. Gen Comp Endocrinol, 2012 Oct 1. PMID 22885556
  2. Insights into stem cell factor chemotactic guidance of neural crest cells revealed by a real-time directionality-based assay. Rovasio RA, et al. Eur J Cell Biol, 2012 May. PMID 22382085
  3. Epidermal growth factor (EGF) receptor ligands in the chicken ovary: I. Evidence for heparin-binding EGF-like growth factor (HB-EGF) as a potential oocyte-derived signal to control granulosa cell proliferation and HB-EGF and kit ligand expression. Wang Y, et al. Endocrinology, 2007 Jul. PMID 17395697
  4. Sequence of a cDNA encoding chicken stem cell factor. Zhou JH, et al. Gene, 1993 May 30. PMID 7684722
  5. Gene Duplication of the zebrafish kit ligand and partitioning of melanocyte development functions to kit ligand a. Hultman KA, et al. PLoS Genet, 2007 Jan 26. PMID 17257055, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. KL mRNA expression during follicle maturation in the domestic hen was characterized.
    Title: Expression and regulation of Kit ligand in the ovary of the hen.
  2. epidermal SCF molecule may be involved in the chemotactic guidance mechanism of in vivo NCCs.
    Title: Insights into stem cell factor chemotactic guidance of neural crest cells revealed by a real-time directionality-based assay.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables stem cell factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
kit ligand
Names
C-kit ligand
KIT ligand precursor form 1
KIT ligand precursor form 4
MGF
SCF
mast cell growth factor
stem cell factor
NP_001098785.1
NP_990461.1
XP_046762731.1
XP_046769154.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105315.1 → NP_001098785.1  kit ligand isoform 2 precursor

    See identical proteins and their annotated locations for NP_001098785.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ870922
    UniProtKB/TrEMBL
    Q009U4
    Related
    ENSGALP00010015661.1, ENSGALT00010027407.1
    Conserved Domains (1) summary
    pfam02404
    Location:1 → 227
    SCF; Stem cell factor

  2. NM_205130.2 → NP_990461.1  kit ligand isoform 1 precursor

    See identical proteins and their annotated locations for NP_990461.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000012
    UniProtKB/Swiss-Prot
    Q09108
    UniProtKB/TrEMBL
    A0A8V0Y9L0, Q009U6
    Related
    ENSGALP00010015667.1, ENSGALT00010027413.1
    Conserved Domains (1) summary
    pfam02404
    Location:1 → 287
    SCF; Stem cell factor

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    43031098..43086555 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046913198.1 → XP_046769154.1  kit ligand isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y9L3
    Related
    ENSGALP00010015663.1, ENSGALT00010027410.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    43373018..43428460 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046906775.1 → XP_046762731.1  kit ligand isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y9L3
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q09108.1 GenPept UniProtKB/Swiss-Prot:Q09108

Gene LinkOut

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