VDR vitamin D (1,25- dihydroxyvitamin D3) receptor [Gallus gallus (chicken)] - Gene

Summary

Symbol: VDRprovided by CGNC
Full Name: vitamin D (1,25- dihydroxyvitamin D3) receptorprovided by CGNC
Primary source: CGNC:10190
See related: Ensembl:ENSGALG00010024416
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 34

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	34	NC_052565.1 (1098821..1128668, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	34	NC_052606.1 (1042532..1072353, complement)

Chromosome 34 - NC_052565.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The knockdown of chicken PIWIL1 and PIWIL2 decreased the expression of piRNA-linked gene VDR in the primordial germ cells.
Title: Small non-coding RNA profiling and the role of piRNA pathway genes in the protection of chicken primordial germ cells.
Analysus of 3 uncorrelated genetic markers (single nucleotide polymorphisms) in the vitamin D receptor gene for association with Marek's disease resistance.
Title: Association of a marker in the vitamin D receptor gene with Marek's disease resistance in poultry.
Differential VDR expression in the epididymal region segments reveals that several extratesticular ducts may be targets for vitamin D3 action; vitamin D3 may have a regional-specific function, such as calcium transport.
Title: Distribution of vitamin D3 receptor in the epididymal region of roosters (Gallus domesticus) is cell and segment specific.
endogenous TRPC3-like proteins and the VDR participate in the modulation of CCE by 1alpha,25(OH)2D3 in muscle cells, which could be mediated by an interaction between these proteins
Title: TRPC3-like protein and vitamin D receptor mediate 1alpha,25(OH)2D3-induced SOC influx in muscle cells.
Polymorphisms within the VDR gene are associated with bone mineral content of the humerus at 35 weeks of age.
Title: Polymorphisms in vitamin D receptor, osteopontin, insulin-like growth factor 1 and insulin, and their associations with bone, egg and growth traits in a layer--broiler cross in chickens.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables nuclear receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables vitamin D response element binding	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in multicellular organism development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: vitamin D3 receptor

Names: 1,25-dihydroxyvitamin D3 receptor; nuclear receptor subfamily 1 group I member 1; vitamin D receptor

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205098.2 → NP_990429.2 vitamin D3 receptor

Status: PROVISIONAL

Source sequence(s)

JAENSK010000489

UniProtKB/Swiss-Prot

O42392

UniProtKB/TrEMBL

A0A8V0ZSB9

Related

ENSGALP00010036378.1, ENSGALT00010059574.1

Conserved Domains (2) summary

cd06933
Location:147 → 450

NR_LBD_VDR; The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily

cd06955
Location:39 → 145

NR_DBD_VDR; DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052565.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

1098821..1128668 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015272604.4 → XP_015128090.1 vitamin D3 receptor isoform X1

UniProtKB/Swiss-Prot

O42392

UniProtKB/TrEMBL

A0A8V0ZSB9

Related

ENSGALP00010036375.1, ENSGALT00010059571.1

Conserved Domains (2) summary

cd06933
Location:147 → 450

NR_LBD_VDR; The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily

cd06955
Location:39 → 145

NR_DBD_VDR; DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers
XM_046904956.1 → XP_046760912.1 vitamin D3 receptor isoform X2
XM_046904950.1 → XP_046760906.1 vitamin D3 receptor isoform X1

UniProtKB/TrEMBL

A0A8V0ZSB9
XM_046904948.1 → XP_046760904.1 vitamin D3 receptor isoform X1

UniProtKB/TrEMBL

A0A8V0ZSB9
XM_046904954.1 → XP_046760910.1 vitamin D3 receptor isoform X1

UniProtKB/TrEMBL

A0A8V0ZSB9
XM_046904953.1 → XP_046760909.1 vitamin D3 receptor isoform X1

UniProtKB/TrEMBL

A0A8V0ZSB9
XM_046904952.1 → XP_046760908.1 vitamin D3 receptor isoform X1

UniProtKB/TrEMBL

A0A8V0ZSB9
XM_046904951.1 → XP_046760907.1 vitamin D3 receptor isoform X1

UniProtKB/TrEMBL

A0A8V0ZSB9
XM_046904949.1 → XP_046760905.1 vitamin D3 receptor isoform X1

UniProtKB/TrEMBL

A0A8V0ZSB9
XM_046904955.1 → XP_046760911.1 vitamin D3 receptor isoform X1

UniProtKB/TrEMBL

A0A8V0ZSB9
XM_015272605.4 → XP_015128091.1 vitamin D3 receptor isoform X1

UniProtKB/Swiss-Prot

O42392

UniProtKB/TrEMBL

A0A8V0ZSB9

Conserved Domains (2) summary

cd06933
Location:147 → 450

NR_LBD_VDR; The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily

cd06955
Location:39 → 145

NR_DBD_VDR; DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers
XM_015272607.4 → XP_015128093.1 vitamin D3 receptor isoform X3

UniProtKB/Swiss-Prot

O42392

Conserved Domains (2) summary

cd06933
Location:79 → 382

NR_LBD_VDR; The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily

cl02596
Location:5 → 77

NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers