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HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [ Gallus gallus (chicken) ]

Gene ID: 395929, updated on 3-Apr-2024

Summary

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Symbol
HADHAprovided by CGNC
Full Name
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunitprovided by CGNC
Primary source
CGNC:12383
See related
Ensembl:ENSGALG00010009551
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
21
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (104751511..104775672, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (104516195..104540325, complement)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene kinesin family member 3C Neighboring gene RAB10, member RAS oncogene family Neighboring gene GRB2 associated regulator of MAPK1 subtype 2 Neighboring gene hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit Neighboring gene sterile alpha motif domain-containing protein 12-like Neighboring gene microRNA 6578

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD+ binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables enoyl-CoA hydratase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables long-chain-3-hydroxyacyl-CoA dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fatty acid beta-oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of mitochondrial fatty acid beta-oxidation multienzyme complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
trifunctional enzyme subunit alpha, mitochondrial
Names
CFR-associated protein p70
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
NP_990387.3
XP_015140578.2
XP_046769127.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205056.3 → NP_990387.3  trifunctional enzyme subunit alpha, mitochondrial

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000070
    Related
    ENSGALP00010013170.1, ENSGALT00010022786.1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    104751511..104775672 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015285092.4 → XP_015140578.2  trifunctional enzyme subunit alpha, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y492, O57660
    Related
    ENSGALP00010013161.1, ENSGALT00010022774.1
    Conserved Domains (1) summary
    TIGR02441
    Location:18 → 753
    fa_ox_alpha_mit; fatty acid oxidation complex, alpha subunit, mitochondrial

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    104516195..104540325 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046913171.1 → XP_046769127.1  trifunctional enzyme subunit alpha, mitochondrial isoform X1

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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