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CNTFR ciliary neurotrophic factor receptor [ Gallus gallus (chicken) ]

Gene ID: 395885, updated on 3-Apr-2024

Summary

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Symbol
CNTFRprovided by CGNC
Full Name
ciliary neurotrophic factor receptorprovided by CGNC
Primary source
CGNC:20242
See related
Ensembl:ENSGALG00010009400
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Z
Exon count:
19
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (8672196..8843287)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (8672196..8843287)

Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121108637 Neighboring gene uncharacterized LOC121108638 Neighboring gene interleukin 11 receptor subunit alpha Neighboring gene uncharacterized LOC112530623 Neighboring gene C-C motif chemokine ligand 19

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Analysis of function and expression of the chick GPA receptor (GPAR alpha) suggests multiple roles in neuronal development. Heller S, et al. Development, 1995 Aug. PMID 7671828
  2. Cloning of the alpha component of the chick ciliary neurotrophic factor receptor: developmental expression and down-regulation in denervated skeletal muscle. Ip FC, et al. J Neurochem, 1995 Dec. PMID 7595532
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ciliary neurotrophic factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of CNTFR-CLCF1 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of ciliary neurotrophic factor receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ciliary neurotrophic factor receptor subunit alpha
Names
CNTF receptor subunit alpha
CNTFR-alpha
GPA receptor subunit alpha
GPAR-alpha
growth promoting activity (GPA) receptor alpha; GPARalpha
growth-promoting activity receptor subunit alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205028.2 → NP_990359.2  ciliary neurotrophic factor receptor subunit alpha precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000087
    UniProtKB/Swiss-Prot
    P51641
    UniProtKB/TrEMBL
    A0A8V0XXF6
    Related
    ENSGALP00010013088.1, ENSGALT00010022672.1
    Conserved Domains (2) summary
    smart00408
    Location:37 → 94
    IGc2; Immunoglobulin C-2 Type
    cd00063
    Location:202 → 298
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    8672196..8843287
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046905245.1 → XP_046761201.1  ciliary neurotrophic factor receptor subunit alpha isoform X5

    UniProtKB/TrEMBL
    A0A8V0Y3N1

  2. XM_040655429.2 → XP_040511363.1  ciliary neurotrophic factor receptor subunit alpha isoform X3

    UniProtKB/Swiss-Prot
    P51641
    UniProtKB/TrEMBL
    A0A8V0XXF6
    Conserved Domains (2) summary
    smart00408
    Location:37 → 94
    IGc2; Immunoglobulin C-2 Type
    cd00063
    Location:202 → 298
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  3. XM_046905250.1 → XP_046761206.1  ciliary neurotrophic factor receptor subunit alpha isoform X3

    UniProtKB/Swiss-Prot
    P51641

  4. XM_046905247.1 → XP_046761203.1  ciliary neurotrophic factor receptor subunit alpha isoform X5

    UniProtKB/TrEMBL
    A0A8V0Y3N1

  5. XM_040655426.2 → XP_040511360.2  ciliary neurotrophic factor receptor subunit alpha isoform X3

    UniProtKB/Swiss-Prot
    P51641
    Related
    ENSGALP00010013085.1, ENSGALT00010022669.1

  6. XM_015277243.4 → XP_015132729.2  ciliary neurotrophic factor receptor subunit alpha isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y1Y3
    Related
    ENSGALP00010012961.1, ENSGALT00010022500.1

  7. XM_040655425.2 → XP_040511359.1  ciliary neurotrophic factor receptor subunit alpha isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y3S7
    Conserved Domains (2) summary
    smart00408
    Location:122 → 179
    IGc2; Immunoglobulin C-2 Type
    cd00063
    Location:287 → 383
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  8. XM_046905248.1 → XP_046761204.1  ciliary neurotrophic factor receptor subunit alpha isoform X5

    UniProtKB/TrEMBL
    A0A8V0Y3N1
    Related
    ENSGALP00010012949.1, ENSGALT00010022478.1

  9. XM_040655430.1 → XP_040511364.1  ciliary neurotrophic factor receptor subunit alpha isoform X3

    UniProtKB/Swiss-Prot
    P51641
    UniProtKB/TrEMBL
    A0A8V0XXF6
    Conserved Domains (2) summary
    smart00408
    Location:37 → 94
    IGc2; Immunoglobulin C-2 Type
    cd00063
    Location:202 → 298
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  10. XM_040655431.1 → XP_040511365.1  ciliary neurotrophic factor receptor subunit alpha isoform X3

    UniProtKB/Swiss-Prot
    P51641
    UniProtKB/TrEMBL
    A0A8V0XXF6
    Related
    ENSGALP00010013051.1, ENSGALT00010022619.1
    Conserved Domains (2) summary
    smart00408
    Location:37 → 94
    IGc2; Immunoglobulin C-2 Type
    cd00063
    Location:202 → 298
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  11. XM_046905246.1 → XP_046761202.1  ciliary neurotrophic factor receptor subunit alpha isoform X5

    UniProtKB/TrEMBL
    A0A8V0Y3N1

  12. XM_046905249.1 → XP_046761205.1  ciliary neurotrophic factor receptor subunit alpha isoform X3

    UniProtKB/Swiss-Prot
    P51641

  13. XM_040655432.1 → XP_040511366.1  ciliary neurotrophic factor receptor subunit alpha isoform X3

    UniProtKB/Swiss-Prot
    P51641
    UniProtKB/TrEMBL
    A0A8V0XXF6
    Related
    ENSGALP00010012952.1, ENSGALT00010022487.1
    Conserved Domains (2) summary
    smart00408
    Location:37 → 94
    IGc2; Immunoglobulin C-2 Type
    cd00063
    Location:202 → 298
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  14. XM_040655427.2 → XP_040511361.1  ciliary neurotrophic factor receptor subunit alpha isoform X4

    UniProtKB/TrEMBL
    A0A8V0XXF6, A0A8V0Y3L6
    Related
    ENSGALP00010012934.1, ENSGALT00010022462.1
    Conserved Domains (2) summary
    smart00408
    Location:57 → 114
    IGc2; Immunoglobulin C-2 Type
    cd00063
    Location:222 → 318
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    8672196..8843287
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046934813.1 → XP_046790769.1  ciliary neurotrophic factor receptor subunit alpha isoform X5

    UniProtKB/TrEMBL
    A0A8V0Y3N1

  2. XM_046934817.1 → XP_046790773.1  ciliary neurotrophic factor receptor subunit alpha isoform X3

    UniProtKB/Swiss-Prot
    P51641

  3. XM_046934822.1 → XP_046790778.1  ciliary neurotrophic factor receptor subunit alpha isoform X3

    UniProtKB/Swiss-Prot
    P51641

  4. XM_046934815.1 → XP_046790771.1  ciliary neurotrophic factor receptor subunit alpha isoform X5

    UniProtKB/TrEMBL
    A0A8V0Y3N1

  5. XM_046934811.1 → XP_046790767.1  ciliary neurotrophic factor receptor subunit alpha isoform X3

    UniProtKB/Swiss-Prot
    P51641

  6. XM_046934809.1 → XP_046790765.1  ciliary neurotrophic factor receptor subunit alpha isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y1Y3

  7. XM_046934810.1 → XP_046790766.1  ciliary neurotrophic factor receptor subunit alpha isoform X2

  8. XM_046934816.1 → XP_046790772.1  ciliary neurotrophic factor receptor subunit alpha isoform X5

    UniProtKB/TrEMBL
    A0A8V0Y3N1

  9. XM_046934818.1 → XP_046790774.1  ciliary neurotrophic factor receptor subunit alpha isoform X3

    UniProtKB/Swiss-Prot
    P51641

  10. XM_046934819.1 → XP_046790775.1  ciliary neurotrophic factor receptor subunit alpha isoform X3

    UniProtKB/Swiss-Prot
    P51641

  11. XM_046934814.1 → XP_046790770.1  ciliary neurotrophic factor receptor subunit alpha isoform X5

    UniProtKB/TrEMBL
    A0A8V0Y3N1

  12. XM_046934820.1 → XP_046790776.1  ciliary neurotrophic factor receptor subunit alpha isoform X3

    UniProtKB/Swiss-Prot
    P51641

  13. XM_046934821.1 → XP_046790777.1  ciliary neurotrophic factor receptor subunit alpha isoform X3

    UniProtKB/Swiss-Prot
    P51641

  14. XM_046934812.1 → XP_046790768.1  ciliary neurotrophic factor receptor subunit alpha isoform X4

    UniProtKB/TrEMBL
    A0A8V0Y3L6
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P51641.1 GenPept UniProtKB/Swiss-Prot:P51641

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