U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ALDH1A2 aldehyde dehydrogenase 1 family member A2 [ Gallus gallus (chicken) ]

Gene ID: 395844, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
ALDH1A2provided by CGNC
Official Full Name
aldehyde dehydrogenase 1 family member A2provided by CGNC
Primary source
CGNC:3140
See related
Ensembl:ENSGALG00010023060
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
RALDH2; RALDH(II)
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 10
Exon count:
16
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 10 NC_052541.1 (7127145..7182584)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 10 NC_052582.1 (6999857..7055362)

Chromosome 10 - NC_052541.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124417123 Neighboring gene lipase C, hepatic type Neighboring gene uncharacterized LOC107052129 Neighboring gene aquaporin 9 Neighboring gene myocardial zonula adherens protein Neighboring gene cingulin like 1 Neighboring gene transcription factor 12

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. RALDH2, the enzyme for retinoic acid synthesis, mediates meiosis initiation in germ cells of the female embryonic chickens. Yu M, et al. Amino Acids, 2013 Feb. PMID 22733143
  2. Identification of RALDH2 as a visually regulated retinoic acid synthesizing enzyme in the chick choroid. Rada JA, et al. Invest Ophthalmol Vis Sci, 2012 Mar. PMID 22323456, Free PMC Article
  3. Motor neuron-derived retinoid signaling specifies the subtype identity of spinal motor neurons. Sockanathan S, et al. Cell, 1998 Aug 21. PMID 9727493
  4. Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1. Tsukui T, et al. Proc Natl Acad Sci U S A, 1999 Sep 28. PMID 10500184, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. RALDH2 mediates meiosis initiation in germ cells of the female embryonic chickens.
    Title: RALDH2, the enzyme for retinoic acid synthesis, mediates meiosis initiation in germ cells of the female embryonic chickens.
  2. results of this study suggest that RALDH2 is the major retinal dehydrogenase in the chick choroid and is responsible for increased atRA synthesis in response to myopic defocus.
    Title: Identification of RALDH2 as a visually regulated retinoic acid synthesizing enzyme in the chick choroid.
Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aldehyde dehydrogenase (NAD+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
retinal dehydrogenase 2
Names
aldehyde dehydrogenase 1A2
aldehyde dehydrogenase family 1 member A2
retinaldehyde dehydrogenase 2
retinaldehyde-specific dehydrogenase type 2
NP_001384737.1
NP_990326.2
XP_046754866.1
XP_046754867.1
XP_046780471.1
XP_046780472.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001397808.1 → NP_001384737.1  retinal dehydrogenase 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000245
    UniProtKB/TrEMBL
    A0A8V0ZT16
    Related
    ENSGALP00010033978.1, ENSGALT00010056156.1
    Conserved Domains (1) summary
    cd07141
    Location:1 → 416
    ALDH_F1AB_F2_RALDH1; NAD+-dependent retinal dehydrogenase 1, ALDH families 1A, 1B, and 2-like

  2. NM_204995.3 → NP_990326.2  retinal dehydrogenase 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000245
    UniProtKB/Swiss-Prot
    O93344, Q549A6
    Conserved Domains (1) summary
    cd07141
    Location:32 → 512
    ALDH_F1AB_F2_RALDH1; NAD+-dependent retinal dehydrogenase 1, ALDH families 1A, 1B, and 2-like

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052541.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    7127145..7182584
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046898910.1 → XP_046754866.1  retinal dehydrogenase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZT16

  2. XM_046898911.1 → XP_046754867.1  retinal dehydrogenase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZT16

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052582.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    6999857..7055362
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046924515.1 → XP_046780471.1  retinal dehydrogenase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZT16

  2. XM_046924516.1 → XP_046780472.1  retinal dehydrogenase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZT16

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001389368.1: Suppressed sequence

    Description
    NM_001389368.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O93344.2 GenPept UniProtKB/Swiss-Prot:O93344

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous