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PTCH1 patched 1 [ Gallus gallus (chicken) ]

Gene ID: 395806, updated on 3-Apr-2024

Summary

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Symbol
PTCH1provided by CGNC
Full Name
patched 1provided by CGNC
Primary source
CGNC:49488
See related
Ensembl:ENSGALG00010010406
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
PTC; PTC1; PTCH
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Z
Exon count:
26
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (42380208..42445953, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (42380208..42445953, complement)

Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene aminopeptidase O (putative) Neighboring gene microRNA 24-2 Neighboring gene Fanconi anemia complementation group C Neighboring gene uncharacterized LOC112530576 Neighboring gene uncharacterized LOC107052326 Neighboring gene ERCC excision repair 6 like 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Biochemical evidence that patched is the Hedgehog receptor. Marigo V, et al. Nature, 1996 Nov 14. PMID 8906794
  2. Conservation in hedgehog signaling: induction of a chicken patched homolog by Sonic hedgehog in the developing limb. Marigo V, et al. Development, 1996 Apr. PMID 8620849
  3. Male-biased mutation rate and divergence in autosomal, z-linked and w-linked introns of chicken and Turkey. Axelsson E, et al. Mol Biol Evol, 2004 Aug. PMID 15140948
  4. Transcriptome analysis for the chicken based on 19,626 finished cDNA sequences and 485,337 expressed sequence tags. Hubbard SJ, et al. Genome Res, 2005 Jan. PMID 15590942, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hedgehog family protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hedgehog receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables smoothened binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in smoothened signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein patched homolog 1
Names
patched homolog 1
patched protein
patched-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204960.3 → NP_990291.3  protein patched homolog 1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000094
    UniProtKB/Swiss-Prot
    Q90693
    UniProtKB/TrEMBL
    A0A8V0Y5A3
    Related
    ENSGALP00010014125.1, ENSGALT00010024886.1
    Conserved Domains (1) summary
    TIGR00918
    Location:44 → 1206
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    42380208..42445953 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040655421.2 → XP_040511355.1  protein patched homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y5B2
    Conserved Domains (1) summary
    TIGR00918
    Location:4 → 1142
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  2. XM_040655422.2 → XP_040511356.1  protein patched homolog 1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y5B2
    Conserved Domains (1) summary
    TIGR00918
    Location:1 → 1054
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  3. XM_025144670.3 → XP_025000438.2  protein patched homolog 1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y5B2
    Conserved Domains (1) summary
    TIGR00918
    Location:1 → 1054
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  4. XM_040655423.2 → XP_040511357.1  protein patched homolog 1 isoform X3

    Conserved Domains (1) summary
    TIGR00918
    Location:44 → 1151
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    42380208..42445953 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046934805.1 → XP_046790761.1  protein patched homolog 1 isoform X1

  2. XM_046934806.1 → XP_046790762.1  protein patched homolog 1 isoform X2

  3. XM_046934807.1 → XP_046790763.1  protein patched homolog 1 isoform X2

  4. XM_046934808.1 → XP_046790764.1  protein patched homolog 1 isoform X3

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q90693.1 GenPept UniProtKB/Swiss-Prot:Q90693

Gene LinkOut

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