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AXIN1 axin 1 [ Gallus gallus (chicken) ]

Gene ID: 395786, updated on 3-Apr-2024

Summary

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Symbol
AXIN1provided by CGNC
Full Name
axin 1provided by CGNC
Primary source
CGNC:49477
See related
Ensembl:ENSGALG00010016911
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
AXIN; axin-1; AXIN1-RGS
Orthologs
human mouse all
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Genomic context

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See AXIN1 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
12
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 14 NC_052545.1 (12159297..12235940)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 14 NC_052586.1 (12154929..12231545)

Chromosome 14 - NC_052545.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 8A Neighboring gene mitochondrial ribosomal protein L28 Neighboring gene uncharacterized LOC121106767 Neighboring gene uncharacterized LOC121106768 Neighboring gene protein disulfide isomerase family A member 2 Neighboring gene Rho GDP dissociation inhibitor gamma

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. RNAi-induced targeted silencing of developmental control genes during chicken embryogenesis. Dai F, et al. Dev Biol, 2005 Sep 1. PMID 16055113
  2. Semaphorin3A-induced axonal transport mediated through phosphorylation of Axin-1 by GSK3β. Hida T, et al. Brain Res, 2015 Feb 19. PMID 25528666
  3. The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation. Zeng L, et al. Cell, 1997 Jul 11. PMID 9230313
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
axin-1
Names
axis inhibition protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204944.3 → NP_990275.2  axin-1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000257
    UniProtKB/TrEMBL
    A0A1D5P395, A0A1D5PN57, Q6B3C4
    Related
    ENSGALP00010023787.1, ENSGALT00010040823.1
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:761 → 838
    DIX; DIX domain
    pfam08833
    Location:467 → 503
    Axin_b-cat_bind; Axin beta-catenin binding domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052545.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    12159297..12235940
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046900558.1 → XP_046756514.1  axin-1 isoform X1

    UniProtKB/TrEMBL
    A0A1D5P395, A0A1D5PN57

  2. XM_025155050.3 → XP_025010818.1  axin-1 isoform X1

    UniProtKB/TrEMBL
    A0A1D5P395, A0A1D5PN57, Q6B3C4
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:761 → 838
    DIX; DIX domain
    pfam08833
    Location:467 → 503
    Axin_b-cat_bind; Axin beta-catenin binding domain

  3. XM_046900560.1 → XP_046756516.1  axin-1 isoform X1

    UniProtKB/TrEMBL
    A0A1D5P395, A0A1D5PN57

  4. XM_015294136.4 → XP_015149622.1  axin-1 isoform X1

    UniProtKB/TrEMBL
    A0A1D5P395, A0A1D5PN57, Q6B3C4
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:761 → 838
    DIX; DIX domain
    pfam08833
    Location:467 → 503
    Axin_b-cat_bind; Axin beta-catenin binding domain

  5. XM_046900559.1 → XP_046756515.1  axin-1 isoform X1

    UniProtKB/TrEMBL
    A0A1D5P395, A0A1D5PN57

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052586.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    12154929..12231545
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046927289.1 → XP_046783245.1  axin-1 isoform X1

  2. XM_046927288.1 → XP_046783244.1  axin-1 isoform X1

  3. XM_046927291.1 → XP_046783247.1  axin-1 isoform X1

  4. XM_046927287.1 → XP_046783243.1  axin-1 isoform X1

  5. XM_046927290.1 → XP_046783246.1  axin-1 isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O42400.1 GenPept UniProtKB/Swiss-Prot:O42400

Gene LinkOut

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