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FZD3 frizzled class receptor 3 [ Gallus gallus (chicken) ]

Gene ID: 395572, updated on 3-Apr-2024

Summary

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Symbol
FZD3provided by CGNC
Full Name
frizzled class receptor 3provided by CGNC
Primary source
CGNC:12460
See related
Ensembl:ENSGALG00010010949
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
FZ-3
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (105634168..105686155)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (105397822..105449808)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene elongator acetyltransferase complex subunit 3 Neighboring gene F-box protein 16 Neighboring gene exostosin like glycosyltransferase 3 Neighboring gene integrator complex subunit 9

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Differential expression of the frizzled family involved in Wnt signaling during chick limb development. Nohno T, et al. Cell Mol Biol (Noisy-le-grand), 1999 Jul. PMID 10512196
  2. A comprehensive collection of chicken cDNAs. Boardman PE, et al. Curr Biol, 2002 Nov 19. PMID 12445392
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Wnt receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in non-canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
frizzled-3
Names
frizzled family receptor 3
frizzled homolog 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271940.4 → NP_001258869.1  frizzled-3 precursor

    See identical proteins and their annotated locations for NP_001258869.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    JAENSK010000070
    UniProtKB/TrEMBL
    A0A1D5NTJ0, A0A8V0YFR2
    Related
    ENSGALP00010014845.1, ENSGALT00010026221.1
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  2. NM_001271941.4 → NP_001258870.1  frizzled-3 precursor

    See identical proteins and their annotated locations for NP_001258870.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    JAENSK010000070
    UniProtKB/TrEMBL
    A0A1D5NTJ0, A0A8V0YFR2
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    105634168..105686155
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046938426.1 → XP_046794382.1  frizzled-3 isoform X1

    UniProtKB/TrEMBL
    A0A1D5NTJ0

  2. XM_040696765.2 → XP_040552699.1  frizzled-3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y8V5, A0A8V0YFR2
    Related
    ENSGALP00010014844.1, ENSGALT00010026220.1
    Conserved Domains (2) summary
    cd15033
    Location:149 → 469
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors
    cl02447
    Location:20 → 107
    CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    105397822..105449808
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046913002.1 → XP_046768958.1  frizzled-3 isoform X1

    UniProtKB/TrEMBL
    A0A1D5NTJ0

  2. XM_046913003.1 → XP_046768959.1  frizzled-3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y8V5
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9PTW3.1 GenPept UniProtKB/Swiss-Prot:Q9PTW3

Gene LinkOut

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