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WNT11 Wnt family member 11 [ Gallus gallus (chicken) ]

Gene ID: 395562, updated on 5-Mar-2024

Summary

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Official Symbol
WNT11provided by CGNC
Official Full Name
Wnt family member 11provided by CGNC
Primary source
CGNC:546
See related
Ensembl:ENSGALG00010002356
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
WNT-11
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (193749407..193811820)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (193820353..193882524)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene transfer RNA proline (anticodon UGG) Neighboring gene transfer RNA proline (anticodon AGG) Neighboring gene UV radiation resistance associated Neighboring gene ADP-ribosyltransferase 1G

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Avian facial morphogenesis is regulated by c-Jun N-terminal kinase/planar cell polarity (JNK/PCP) wingless-related (WNT) signaling. Geetha-Loganathan P, et al. J Biol Chem, 2014 Aug 29. PMID 25008326, Free PMC Article
  2. WNT11 acts as a directional cue to organize the elongation of early muscle fibres. Gros J, et al. Nature, 2009 Jan 29. PMID 18987628
  3. Wnt signalling regulates myogenic differentiation in the developing avian wing. Anakwe K, et al. Development, 2003 Aug. PMID 12810597
  4. A chicken Wnt gene, Wnt-11, is involved in dermal development. Tanda N, et al. Biochem Biophys Res Commun, 1995 Jun 6. PMID 7779076
  5. Regulation of ectodermal Wnt6 expression by the neural tube is transduced by dermomyotomal Wnt11: a mechanism of dermomyotomal lip sustainment. Geetha-Loganathan P, et al. Development, 2006 Aug. PMID 16818447

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Wnt11 is required for dense dermis and subsequent cutaneous appendage formation, by influencing the cell fate decision of the cells in the dorsomedial lip.
    Title: Wnt11 is required for oriented migration of dermogenic progenitor cells from the dorsomedial lip of the avian dermomyotome.
  2. during early chick myogenesis WNT11 has an essential role in the oriented elongation of the myocytes
    Title: WNT11 acts as a directional cue to organize the elongation of early muscle fibres.
  3. Wnt11 and Wnt6 act as factors maintaining the epithelial nature of the dorsomedial and ventrolateral lips of the dermomyotome, respectively, during dermomyotomal growth.
    Title: Regulation of ectodermal Wnt6 expression by the neural tube is transduced by dermomyotomal Wnt11: a mechanism of dermomyotomal lip sustainment.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables frizzled binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell fate commitment IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein Wnt-11
Names
Wnt-11 protein
wingless-type MMTV integration site family, member 11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204784.1 → NP_990115.1  protein Wnt-11 precursor

    See identical proteins and their annotated locations for NP_990115.1

    Status: PROVISIONAL

    Source sequence(s)
    D31901
    UniProtKB/Swiss-Prot
    P49339
    Conserved Domains (1) summary
    smart00097
    Location:47 → 354
    WNT1; found in Wnt-1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    193749407..193811820
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040650634.2 → XP_040506568.1  protein Wnt-11 isoform X3

    UniProtKB/TrEMBL
    A0A8V0XFN1
    Related
    ENSGALP00010003182.1, ENSGALT00010005343.1
    Conserved Domains (1) summary
    cd19343
    Location:51 → 308
    Wnt_Wnt11; Wnt domain found in protein Wnt-11 and similar proteins

  2. XM_015280851.4 → XP_015136337.1  protein Wnt-11 isoform X1

    UniProtKB/Swiss-Prot
    P49339
    Related
    ENSGALP00010003181.1, ENSGALT00010005342.1
    Conserved Domains (1) summary
    smart00097
    Location:47 → 354
    WNT1; found in Wnt-1

  3. XM_015280852.4 → XP_015136338.1  protein Wnt-11 isoform X2

    UniProtKB/TrEMBL
    A0A8V0X957
    Related
    ENSGALP00010003179.1, ENSGALT00010005340.1
    Conserved Domains (1) summary
    smart00097
    Location:47 → 326
    WNT1; found in Wnt-1

  4. XM_040650658.2 → XP_040506592.1  protein Wnt-11 isoform X4

    Conserved Domains (1) summary
    cd19343
    Location:1 → 289
    Wnt_Wnt11; Wnt domain found in protein Wnt-11 and similar proteins

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    193820353..193882524
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046906643.1 → XP_046762599.1  protein Wnt-11 isoform X3

    UniProtKB/TrEMBL
    A0A8V0XFN1

  2. XM_046906641.1 → XP_046762597.1  protein Wnt-11 isoform X1

    UniProtKB/Swiss-Prot
    P49339

  3. XM_046906642.1 → XP_046762598.1  protein Wnt-11 isoform X2

    UniProtKB/TrEMBL
    A0A8V0X957

  4. XM_046906644.1 → XP_046762600.1  protein Wnt-11 isoform X4

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P49339.1 GenPept UniProtKB/Swiss-Prot:P49339

Gene LinkOut

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