WNT4 Wnt family member 4 [Gallus gallus (chicken)] - Gene

Summary

Symbol: WNT4provided by CGNC
Full Name: Wnt family member 4provided by CGNC
Primary source: CGNC:3556
See related: Ensembl:ENSGALG00010016957
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: WNT-4
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 21

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	21	NC_052552.1 (6295870..6309892)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	21	NC_052593.1 (6330785..6344816)

Chromosome 21 - NC_052552.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

WNT4 likely has crucial roles in development and function of oviduct as well as initiation of ovarian carcinogenesis in laying hens.
Title: Avian WNT4 in the female reproductive tracts: potential role of oviduct development and ovarian carcinogenesis.
Studied Wnt4 & Wnt4a expression patterns in chick embryo nervous system
Title: Wnt expression patterns in chick embryo nervous system.
The present results are identical to those of myostatin knockout, suggesting that Wnt4 is acting against myostatin as an antagonizing signal for myostatin.
Title: Involvement of Wnt4 signaling during myogenic proliferation and differentiation of skeletal muscle.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cytokine activity	IEA Inferred from Electronic Annotation more info	PubMed
enables frizzled binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in canonical Wnt signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell fate commitment	IEA Inferred from Electronic Annotation more info	PubMed
involved_in multicellular organism development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in neuron differentiation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: protein Wnt-4

Names: Wnt-4 protein; wingless-type MMTV integration site family member 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.