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STAT5A signal transducer and activator of transcription 5A [ Gallus gallus (chicken) ]

Gene ID: 395556, updated on 11-Apr-2024

Summary

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Symbol
STAT5Aprovided by CGNC
Full Name
signal transducer and activator of transcription 5Aprovided by CGNC
Primary source
CGNC:49373
See related
Ensembl:ENSGALG00010023347
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
STAT5; STAT5B
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Genomic context

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Location:
chromosome: 27
Exon count:
25
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 27 NC_052558.1 (4873140..4888437, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 27 NC_052599.1 (6035211..6050505, complement)

Chromosome 27 - NC_052558.1Genomic Context describing neighboring genes Neighboring gene phospholipase C, delta 4 Neighboring gene microRNA mir-12256 Neighboring gene GH3 domain containing Neighboring gene microRNA mir-12257 Neighboring gene signal transducer and activator of transcription 3 Neighboring gene polymerase I and transcript release factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Single nucleotide polymorphism in the STAT5b gene is associated with body weight and reproductive traits of the Jinghai Yellow chicken. Zhao XH, et al. Mol Biol Rep, 2012 Apr. PMID 21766180
  2. Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation. Kieslinger M, et al. Genes Dev, 2000 Jan 15. PMID 10652277, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. STAT5b gene may be served as a potential genetic marker for growth and reproduction traits evaluation of the Jinghai Yellow chicken.
    Title: Single nucleotide polymorphism in the STAT5b gene is associated with body weight and reproductive traits of the Jinghai Yellow chicken.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in growth hormone receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to peptide hormone IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal transducer and activator of transcription 5A
Names
signal transducer and activator of transcription 5B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204779.1 → NP_990110.1  signal transducer and activator of transcription 5A

    See identical proteins and their annotated locations for NP_990110.1

    Status: PROVISIONAL

    Source sequence(s)
    AF074248
    UniProtKB/TrEMBL
    A0A8V0ZMK5, O93378
    Conserved Domains (4) summary
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:2 → 124
    STAT_int; STAT protein, protein interaction domain
    cl15255
    Location:573 → 717
    SH2; Src homology 2 (SH2) domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052558.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    4873140..4888437 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046904332.1 → XP_046760288.1  signal transducer and activator of transcription 5A isoform X2

    UniProtKB/TrEMBL
    B9VVJ4

  2. XM_046904331.1 → XP_046760287.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    O93378

  3. XM_015299592.4 → XP_015155078.1  signal transducer and activator of transcription 5A isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZMK5, B9VVJ4
    Conserved Domains (4) summary
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:2 → 124
    STAT_int; STAT protein, protein interaction domain
    cl15255
    Location:573 → 712
    SH2; Src homology 2 (SH2) domain

  4. XM_046904330.1 → XP_046760286.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    O93378

  5. XM_040653113.2 → XP_040509047.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZMK5, O93378
    Related
    ENSGALP00010034628.1, ENSGALT00010056946.1
    Conserved Domains (4) summary
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:2 → 124
    STAT_int; STAT protein, protein interaction domain
    cl15255
    Location:573 → 717
    SH2; Src homology 2 (SH2) domain

  6. XM_040653115.2 → XP_040509049.1  signal transducer and activator of transcription 5A isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZMK5, B9VVJ4
    Related
    ENSGALP00010034624.1, ENSGALT00010056941.1
    Conserved Domains (4) summary
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:2 → 124
    STAT_int; STAT protein, protein interaction domain
    cl15255
    Location:573 → 712
    SH2; Src homology 2 (SH2) domain

  7. XM_015299590.4 → XP_015155076.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZMK5, O93378
    Related
    ENSGALP00010034620.1, ENSGALT00010056934.1
    Conserved Domains (4) summary
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:2 → 124
    STAT_int; STAT protein, protein interaction domain
    cl15255
    Location:573 → 717
    SH2; Src homology 2 (SH2) domain

  8. XM_046904329.1 → XP_046760285.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    O93378

  9. XM_046904328.1 → XP_046760284.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    O93378

  10. XM_040653114.2 → XP_040509048.1  signal transducer and activator of transcription 5A isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZMK5, B9VVJ4
    Conserved Domains (4) summary
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:2 → 124
    STAT_int; STAT protein, protein interaction domain
    cl15255
    Location:573 → 712
    SH2; Src homology 2 (SH2) domain

  11. XM_015299591.4 → XP_015155077.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZMK5, O93378
    Related
    ENSGALP00010034617.1, ENSGALT00010056929.1
    Conserved Domains (4) summary
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:2 → 124
    STAT_int; STAT protein, protein interaction domain
    cl15255
    Location:573 → 717
    SH2; Src homology 2 (SH2) domain

  12. XM_046904327.1 → XP_046760283.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    O93378

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052599.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    6035211..6050505 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046933285.1 → XP_046789241.1  signal transducer and activator of transcription 5A isoform X2

    UniProtKB/TrEMBL
    B9VVJ4

  2. XM_046933281.1 → XP_046789237.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    O93378

  3. XM_046933282.1 → XP_046789238.1  signal transducer and activator of transcription 5A isoform X2

    UniProtKB/TrEMBL
    B9VVJ4

  4. XM_046933280.1 → XP_046789236.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    O93378

  5. XM_046933278.1 → XP_046789234.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    O93378

  6. XM_046933284.1 → XP_046789240.1  signal transducer and activator of transcription 5A isoform X2

    UniProtKB/TrEMBL
    B9VVJ4

  7. XM_046933277.1 → XP_046789233.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    O93378

  8. XM_046933279.1 → XP_046789235.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    O93378

  9. XM_046933283.1 → XP_046789239.1  signal transducer and activator of transcription 5A isoform X2

    UniProtKB/TrEMBL
    B9VVJ4

  10. XM_046933276.1 → XP_046789232.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    O93378
Nucleotide Protein Strain
Heading Accession and Version

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