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RDX radixin [ Gallus gallus (chicken) ]

Gene ID: 395511, updated on 5-Mar-2024

Summary

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Official Symbol
RDXprovided by CGNC
Official Full Name
radixinprovided by CGNC
Primary source
CGNC:49356
See related
Ensembl:ENSGALG00010005363
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
15
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (179478699..179514342)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (179511202..179546849)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121109053 Neighboring gene uncharacterized LOC124417158 Neighboring gene ferredoxin 1 Neighboring gene zinc finger CCCH-type containing 12C Neighboring gene uncharacterized LOC121107599 Neighboring gene translation initiation factor IF-2-like Neighboring gene C11orf87 homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning and expression profile of chicken radixin. Li W, et al. Biochim Biophys Acta, 2000 Apr 25. PMID 10760599
  2. Radixin is a constituent of stereocilia in hair cells. Pataky F, et al. Proc Natl Acad Sci U S A, 2004 Feb 24. PMID 14983055, Free PMC Article
  3. Activation of ezrin/radixin/moesin mediates attractive growth cone guidance through regulation of growth cone actin and adhesion receptors. Marsick BM, et al. J Neurosci, 2012 Jan 4. PMID 22219290, Free PMC Article
  4. NHE-RF, a regulatory cofactor for Na(+)-H+ exchange, is a common interactor for merlin and ERM (MERM) proteins. Murthy A, et al. J Biol Chem, 1998 Jan 16. PMID 9430655
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of early endosome to late endosome transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein localization to early endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of organelle assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in apical part of cell IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in filopodium IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in microvillus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
radixin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204751.2 → NP_990082.2  radixin

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000027
    UniProtKB/Swiss-Prot
    Q9PU45
    Related
    ENSGALP00010007297.1, ENSGALT00010012733.1
    Conserved Domains (3) summary
    smart00295
    Location:7 → 206
    B41; Band 4.1 homologues
    cd13194
    Location:200 → 296
    FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
    TIGR02168
    Location:307 → 583
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    179478699..179514342
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040649097.2 → XP_040505031.1  radixin isoform X1

    UniProtKB/Swiss-Prot
    Q9PU45
    Conserved Domains (3) summary
    smart00295
    Location:7 → 206
    B41; Band 4.1 homologues
    cd13194
    Location:200 → 296
    FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
    TIGR02168
    Location:307 → 583
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  2. XM_040649071.2 → XP_040505005.1  radixin isoform X1

    UniProtKB/Swiss-Prot
    Q9PU45
    Conserved Domains (3) summary
    smart00295
    Location:7 → 206
    B41; Band 4.1 homologues
    cd13194
    Location:200 → 296
    FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
    TIGR02168
    Location:307 → 583
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  3. XM_015277633.3 → XP_015133119.2  radixin isoform X2

    Conserved Domains (3) summary
    smart00295
    Location:27 → 70
    B41; Band 4.1 homologues
    cd13194
    Location:64 → 160
    FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
    TIGR02168
    Location:171 → 447
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    179511202..179546849
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9PU45.1 GenPept UniProtKB/Swiss-Prot:Q9PU45

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