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FGF18 fibroblast growth factor 18 [ Gallus gallus (chicken) ]

Gene ID: 395453, updated on 3-Apr-2024

Summary

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Symbol
FGF18provided by CGNC
Full Name
fibroblast growth factor 18provided by CGNC
Primary source
CGNC:49328
See related
Ensembl:ENSGALG00010010399
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
FGF-18
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 13
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 13 NC_052544.1 (2837003..2902497, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 13 NC_052585.1 (2846994..2914096, complement)

Chromosome 13 - NC_052544.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101748278 Neighboring gene uncharacterized LOC121106724 Neighboring gene uncharacterized LOC101748409 Neighboring gene nucleophosmin Neighboring gene T cell leukemia homeobox 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Interactions between FGF18 and retinoic acid regulate differentiation of chick embryo limb myoblasts. Mok GF, et al. Dev Biol, 2014 Dec 15. PMID 25446536
  2. Involvement of fibroblast growth factor (FGF)18-FGF8 signaling in specification of left-right asymmetry and brain and limb development of the chick embryo. Ohuchi H, et al. Mech Dev, 2000 Jul. PMID 10906450

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Interactions between FGF18 and retinoic acid regulate differentiation of chick embryo limb myoblasts.
    Title: Interactions between FGF18 and retinoic acid regulate differentiation of chick embryo limb myoblasts.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables type 1 fibroblast growth factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables type 2 fibroblast growth factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in animal organ morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fibroblast growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fibroblast growth factor 18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001398087.1 → NP_001385016.1  fibroblast growth factor 18 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000256
    Conserved Domains (1) summary
    pfam00167
    Location:53 → 175
    FGF; Fibroblast growth factor

  2. NM_001398088.1 → NP_001385017.1  fibroblast growth factor 18 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000256
    Conserved Domains (1) summary
    pfam00167
    Location:99 → 221
    FGF; Fibroblast growth factor

  3. NM_001398089.1 → NP_001385018.1  fibroblast growth factor 18 isoform 4 precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000256
    UniProtKB/TrEMBL
    A0A8V0Y940
    Related
    ENSGALP00010014109.1, ENSGALT00010024867.1
    Conserved Domains (1) summary
    pfam00167
    Location:99 → 221
    FGF; Fibroblast growth factor

  4. NM_204714.2 → NP_990045.1  fibroblast growth factor 18 isoform 1 precursor

    See identical proteins and their annotated locations for NP_990045.1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000256
    UniProtKB/TrEMBL
    A0A8V0Y580, Q9I950
    Related
    ENSGALP00010014111.1, ENSGALT00010024869.1
    Conserved Domains (1) summary
    pfam00167
    Location:53 → 175
    FGF; Fibroblast growth factor

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052544.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    2837003..2902497 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040646847.1 → XP_040502781.1  fibroblast growth factor 18 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y580
    Related
    ENSGALP00010014105.1, ENSGALT00010024863.1
    Conserved Domains (1) summary
    pfam00167
    Location:30 → 152
    FGF; Fibroblast growth factor

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052585.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    2846994..2914096 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046926823.1 → XP_046782779.1  fibroblast growth factor 18 isoform X1

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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