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ITPR1 inositol 1,4,5-trisphosphate receptor type 1 [ Gallus gallus (chicken) ]

Gene ID: 395412, updated on 11-Apr-2024

Summary

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Symbol
ITPR1provided by CGNC
Full Name
inositol 1,4,5-trisphosphate receptor type 1provided by CGNC
Primary source
CGNC:49305
See related
Ensembl:ENSGALG00010021688
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
64
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 12 NC_052543.1 (18584390..18735101)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 12 NC_052584.1 (18622558..18773247)

Chromosome 12 - NC_052543.1Genomic Context describing neighboring genes Neighboring gene SET domain and mariner transposase fusion gene Neighboring gene sulfatase modifying factor 1 Neighboring gene uncharacterized LOC112533364 Neighboring gene uncharacterized LOC121106666

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulation of skeletal muscle fiber type and slow myosin heavy chain 2 gene expression by inositol trisphosphate receptor 1. Jordan T, et al. J Cell Sci, 2005 May 15. PMID 15870113

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. IP3R1 activity regulates muscle fiber type-specific gene expression in innervated muscle fibers.
    Title: Regulation of skeletal muscle fiber type and slow myosin heavy chain 2 gene expression by inositol trisphosphate receptor 1.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inositol 1,4,5 trisphosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables inositol 1,4,5-trisphosphate-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
inositol 1,4,5-trisphosphate receptor type 1
Names
inositol 1,4,5-triphosphate receptor, type 1
type I inositol triphosphate receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001174059.2 → NP_001167530.1  inositol 1,4,5-trisphosphate receptor type 1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000252
    UniProtKB/TrEMBL
    A0A8V0ZJV7
    Related
    ENSGALP00010031671.1, ENSGALT00010052765.1
    Conserved Domains (6) summary
    smart00472
    Location:231 → 287
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    pfam00520
    Location:2301 → 2563
    Ion_trans; Ion transport protein
    pfam01365
    Location:476 → 665
    RYDR_ITPR; RIH domain
    pfam02815
    Location:232 → 433
    MIR; MIR domain
    pfam08454
    Location:1924 → 2029
    RIH_assoc; RyR and IP3R Homology associated
    pfam08709
    Location:4 → 225
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052543.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    18584390..18735101
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040646080.2 → XP_040502014.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X6

    UniProtKB/TrEMBL
    A0A8V0ZJT0
    Conserved Domains (2) summary
    smart00472
    Location:268 → 324
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    COG1266
    Location:2309 → 2499
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]

  2. XM_040646085.2 → XP_040502019.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X11

    UniProtKB/TrEMBL
    A0A8V0ZJT0
    Conserved Domains (2) summary
    smart00472
    Location:245 → 301
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    COG1266
    Location:2286 → 2476
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]

  3. XM_040646086.2 → XP_040502020.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X13

    UniProtKB/TrEMBL
    A0A8V0ZEC6
    Conserved Domains (2) summary
    smart00472
    Location:231 → 287
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    COG1266
    Location:2272 → 2462
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]

  4. XM_040646075.2 → XP_040502009.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZJT0
    Conserved Domains (2) summary
    smart00472
    Location:282 → 338
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    COG1266
    Location:2323 → 2513
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]

  5. XM_040646076.2 → XP_040502010.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZEC6, A0A8V0ZJT0
    Conserved Domains (2) summary
    smart00472
    Location:282 → 338
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    COG1266
    Location:2322 → 2512
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]

  6. XM_040646077.2 → XP_040502011.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZJT0
    Conserved Domains (2) summary
    smart00472
    Location:282 → 338
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    COG1266
    Location:2322 → 2512
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]

  7. XM_040646079.2 → XP_040502013.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X5

    UniProtKB/TrEMBL
    A0A8V0ZEC6, A0A8V0ZJT0
    Conserved Domains (2) summary
    smart00472
    Location:282 → 338
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    COG1266
    Location:2321 → 2511
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]

  8. XM_015292946.4 → XP_015148432.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X12

    UniProtKB/TrEMBL
    A0A8V0ZEE2
    Related
    ENSGALP00010031664.1, ENSGALT00010052758.1
    Conserved Domains (6) summary
    smart00472
    Location:282 → 338
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    pfam00520
    Location:2352 → 2614
    Ion_trans; Ion transport protein
    pfam01365
    Location:527 → 716
    RYDR_ITPR; RIH domain
    pfam02815
    Location:283 → 484
    MIR; MIR domain
    pfam08454
    Location:1975 → 2080
    RIH_assoc; RyR and IP3R Homology associated
    pfam08709
    Location:18 → 276
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

  9. XM_040646078.2 → XP_040502012.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X4

    UniProtKB/TrEMBL
    A0A8V0ZJT0
    Conserved Domains (2) summary
    smart00472
    Location:282 → 338
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    COG1266
    Location:2322 → 2512
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]

  10. XM_040646081.2 → XP_040502015.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X7

    UniProtKB/TrEMBL
    A0A8V0ZJT0
    Conserved Domains (2) summary
    smart00472
    Location:282 → 338
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    COG1266
    Location:2308 → 2498
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]

  11. XM_040646082.2 → XP_040502016.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X8

    UniProtKB/TrEMBL
    A0A8V0ZJT0
    Conserved Domains (2) summary
    smart00472
    Location:282 → 338
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    COG1266
    Location:2307 → 2497
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]

  12. XM_040646083.2 → XP_040502017.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X9

    UniProtKB/TrEMBL
    A0A8V0ZJT0
    Related
    ENSGALP00010031641.1, ENSGALT00010052735.1
    Conserved Domains (2) summary
    smart00472
    Location:259 → 315
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    COG1266
    Location:2300 → 2490
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]

  13. XM_040646084.2 → XP_040502018.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X10

    UniProtKB/TrEMBL
    A0A8V0ZEC6
    Conserved Domains (2) summary
    smart00472
    Location:245 → 301
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    COG1266
    Location:2286 → 2476
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]

  14. XM_015292951.4 → XP_015148437.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X16

    UniProtKB/TrEMBL
    A0A8V0ZEC6
    Related
    ENSGALP00010031649.1, ENSGALT00010052743.1
    Conserved Domains (6) summary
    smart00472
    Location:245 → 301
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    pfam00520
    Location:2354 → 2616
    Ion_trans; Ion transport protein
    pfam01365
    Location:490 → 679
    RYDR_ITPR; RIH domain
    pfam02815
    Location:246 → 447
    MIR; MIR domain
    pfam08454
    Location:1977 → 2082
    RIH_assoc; RyR and IP3R Homology associated
    pfam08709
    Location:18 → 239
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

  15. XM_015292949.4 → XP_015148435.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X15

    UniProtKB/TrEMBL
    A0A8V0ZS87
    Related
    ENSGALP00010031650.1, ENSGALT00010052744.1
    Conserved Domains (6) summary
    smart00472
    Location:245 → 301
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    pfam00520
    Location:2315 → 2577
    Ion_trans; Ion transport protein
    pfam01365
    Location:490 → 679
    RYDR_ITPR; RIH domain
    pfam02815
    Location:246 → 447
    MIR; MIR domain
    pfam08454
    Location:1938 → 2043
    RIH_assoc; RyR and IP3R Homology associated
    pfam08709
    Location:18 → 239
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

  16. XM_015292952.4 → XP_015148438.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X14

    UniProtKB/TrEMBL
    A0A8V0ZEC6
    Conserved Domains (6) summary
    smart00472
    Location:245 → 301
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    pfam00520
    Location:2340 → 2602
    Ion_trans; Ion transport protein
    pfam01365
    Location:475 → 664
    RYDR_ITPR; RIH domain
    pfam02815
    Location:246 → 432
    MIR; MIR domain
    pfam08454
    Location:1963 → 2068
    RIH_assoc; RyR and IP3R Homology associated
    pfam08709
    Location:18 → 239
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

  17. XM_015292953.4 → XP_015148439.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X17

    UniProtKB/TrEMBL
    A0A8V0ZS87
    Conserved Domains (6) summary
    smart00472
    Location:245 → 301
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    pfam00520
    Location:2300 → 2562
    Ion_trans; Ion transport protein
    pfam01365
    Location:475 → 664
    RYDR_ITPR; RIH domain
    pfam02815
    Location:246 → 432
    MIR; MIR domain
    pfam08454
    Location:1923 → 2028
    RIH_assoc; RyR and IP3R Homology associated
    pfam08709
    Location:18 → 239
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052584.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    18622558..18773247
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046925981.1 → XP_046781937.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X6

  2. XM_046925987.1 → XP_046781943.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X11

  3. XM_046925989.1 → XP_046781945.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X13

  4. XM_046925976.1 → XP_046781932.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X1

  5. XM_046925977.1 → XP_046781933.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X2

  6. XM_046925978.1 → XP_046781934.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X3

  7. XM_046925980.1 → XP_046781936.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X5

  8. XM_046925988.1 → XP_046781944.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X12

  9. XM_046925979.1 → XP_046781935.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X4

  10. XM_046925982.1 → XP_046781938.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X7

  11. XM_046925983.1 → XP_046781939.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X8

  12. XM_046925984.1 → XP_046781940.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X9

  13. XM_046925986.1 → XP_046781942.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X10

  14. XM_046925992.1 → XP_046781948.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X16

  15. XM_046925991.1 → XP_046781947.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X15

  16. XM_046925990.1 → XP_046781946.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X14

  17. XM_046925993.1 → XP_046781949.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X17

Nucleotide Protein
Heading Accession and Version

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