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SNCA synuclein alpha [ Gallus gallus (chicken) ]

Gene ID: 395393, updated on 3-Apr-2024

Summary

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Symbol
SNCAprovided by CGNC
Full Name
synuclein alphaprovided by CGNC
Primary source
CGNC:7901
See related
Ensembl:ENSGALG00010008368
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
6
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (34947237..35014162, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (34899352..34966204, complement)

Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110592 Neighboring gene uncharacterized LOC107051768 Neighboring gene uncharacterized LOC121110593 Neighboring gene uncharacterized LOC121110594 Neighboring gene multimerin 1 Neighboring gene coiled-coil serine rich protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression of alpha-synuclein during eye development of mice (Mus musculus), chick (Gallus gallus domisticus) and fish (Ctenopharyngodon idella) in a comparison study. Seleem AA. Tissue Cell, 2015 Aug. PMID 25997379
  2. Chicken synucleins: cloning and expression in the developing embryo. Tiunova AA, et al. Mech Dev, 2000 Dec. PMID 11091093
  3. Conserved BK channel-protein interactions reveal signals relevant to cell death and survival. Sokolowski B, et al. PLoS One, 2011. PMID 22174833, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The pattern of expression and distribution of alpha-synuclein during the development of ciliary body and iris of mice, chick and fish data concluded that alpha-synuclein has important cellular function during eye development of studied animals.
    Title: Expression of alpha-synuclein during eye development of mice (Mus musculus), chick (Gallus gallus domisticus) and fish (Ctenopharyngodon idella) in a comparison study.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cuprous ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of dopamine secretion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synapse organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synaptic vesicle endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon terminus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alpha-synuclein
Names
synuclein, alpha (non A4 component of amyloid precursor)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204673.2 → NP_990004.1  alpha-synuclein

    See identical proteins and their annotated locations for NP_990004.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000073
    UniProtKB/TrEMBL
    A0A1D5P8R1, A0A8V0XZX6, Q9I9H1
    Related
    ENSGALP00010011573.1, ENSGALT00010020025.1
    Conserved Domains (1) summary
    pfam01387
    Location:1 → 105
    Synuclein; Synuclein

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    34947237..35014162 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015276121.4 → XP_015131607.1  alpha-synuclein isoform X1

    UniProtKB/TrEMBL
    A0A1D5P8R1, A0A8V0XZX6, Q9I9H1
    Conserved Domains (1) summary
    pfam01387
    Location:1 → 105
    Synuclein; Synuclein

  2. XM_025149499.3 → XP_025005267.1  alpha-synuclein isoform X1

    UniProtKB/TrEMBL
    A0A1D5P8R1, A0A8V0XZX6, Q9I9H1
    Related
    ENSGALP00010011576.1, ENSGALT00010020028.1
    Conserved Domains (1) summary
    pfam01387
    Location:1 → 105
    Synuclein; Synuclein

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    34899352..34966204 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046915469.1 → XP_046771425.1  alpha-synuclein isoform X1

    UniProtKB/TrEMBL
    A0A1D5P8R1, Q9I9H1

  2. XM_046915470.1 → XP_046771426.1  alpha-synuclein isoform X1

    UniProtKB/TrEMBL
    A0A1D5P8R1, Q9I9H1
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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