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DYRK1A dual specificity tyrosine phosphorylation regulated kinase 1A [ Gallus gallus (chicken) ]

Gene ID: 395233, updated on 3-Apr-2024

Summary

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Symbol
DYRK1Aprovided by CGNC
Full Name
dual specificity tyrosine phosphorylation regulated kinase 1Aprovided by CGNC
Primary source
CGNC:11992
See related
Ensembl:ENSGALG00010013181
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
MNB
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
14
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (107194219..107279400)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (107283756..107368727)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121107521 Neighboring gene DSCR3 arrestin fold containing Neighboring gene potassium inwardly rectifying channel subfamily J member 6 Neighboring gene uncharacterized LOC121107523

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mnb/Dyrk1A is transiently expressed and asymmetrically segregated in neural progenitor cells at the transition to neurogenic divisions. Hämmerle B, et al. Dev Biol, 2002 Jun 15. PMID 12051815

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine/tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-threonine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein autophosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dual specificity tyrosine-phosphorylation-regulated kinase 1A
Names
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
minibrain protein kinase
NP_989881.2
XP_046756611.1
XP_046756643.1
XP_046762465.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204550.2 → NP_989881.2  dual specificity tyrosine-phosphorylation-regulated kinase 1A

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000020
    UniProtKB/TrEMBL
    F1P0S9, Q8JG32
    Related
    ENSGALP00010018497.1, ENSGALT00010031632.1
    Conserved Domains (1) summary
    cd14226
    Location:140 → 476
    PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    107194219..107279400
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046900687.1 → XP_046756643.1  dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X2

    UniProtKB/TrEMBL
    F1P0S9

  2. XM_046900655.1 → XP_046756611.1  dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    107283756..107368727
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046906509.1 → XP_046762465.1  dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1

Nucleotide Protein
Heading Accession and Version

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