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ROR1 receptor tyrosine kinase like orphan receptor 1 [ Gallus gallus (chicken) ]

Gene ID: 395179, updated on 11-Apr-2024

Summary

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Symbol
ROR1provided by CGNC
Full Name
receptor tyrosine kinase like orphan receptor 1provided by CGNC
Primary source
CGNC:49201
See related
Ensembl:ENSGALG00010024399
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
11
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 8 NC_052539.1 (27567201..27710292)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 8 NC_052580.1 (27579936..27723385)

Chromosome 8 - NC_052539.1Genomic Context describing neighboring genes Neighboring gene ALG6, alpha-1,3-glucosyltransferase Neighboring gene integrin subunit beta 3 binding protein Neighboring gene EF-hand calcium binding domain 7 Neighboring gene phosphoglucomutase 1 Neighboring gene cache domain containing 1 Neighboring gene ribonucleoprotein, PTB binding 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression and regulation of ROR-1 during early avian limb development. Rodriguez-Niedenführ M, et al. Anat Embryol (Berl), 2004 Mar. PMID 14758549

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
inactive tyrosine-protein kinase transmembrane receptor ROR1
Names
tyrosine kinase orphan receptor 1
tyrosine-protein kinase transmembrane receptor ROR1
NP_989840.2
XP_015146426.1
XP_046778236.1
XP_046778237.1
XP_046778238.1
XP_046778239.1
XP_046778240.1
XP_046778241.1
XP_046778242.1
XP_046800195.1
XP_046800196.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204509.2 → NP_989840.2  inactive tyrosine-protein kinase transmembrane receptor ROR1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000239
    UniProtKB/TrEMBL
    Q705C2
    Related
    ENSGALP00010036352.1, ENSGALT00010059533.1
    Conserved Domains (4) summary
    cd07467
    Location:126 → 267
    CRD_TK_ROR1; Cysteine-rich domain of tyrosine kinase-like orphan receptor 1
    smart00130
    Location:271 → 352
    KR; Kringle domain
    pfam07679
    Location:23 → 108
    I-set; Immunoglobulin I-set domain
    cd05090
    Location:427 → 709
    PTKc_Ror1; Catalytic domain of the Protein Tyrosine Kinase, Receptor tyrosine kinase-like Orphan Receptor 1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052539.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    27567201..27710292
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046944240.1 → XP_046800196.1  inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X3

  2. XM_015290940.4 → XP_015146426.1  inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZZK7, A0A8V1A1G5
    Related
    ENSGALP00010036356.1, ENSGALT00010059538.1
    Conserved Domains (6) summary
    cd00096
    Location:81 → 149
    Ig; Immunoglobulin domain
    cd07467
    Location:172 → 313
    CRD_TK_ROR1; Cysteine-rich domain of tyrosine kinase-like orphan receptor 1
    smart00130
    Location:317 → 398
    KR; Kringle domain
    pfam07679
    Location:69 → 154
    I-set; Immunoglobulin I-set domain
    cd05090
    Location:473 → 755
    PTKc_Ror1; Catalytic domain of the Protein Tyrosine Kinase, Receptor tyrosine kinase-like Orphan Receptor 1
    pfam07714
    Location:479 → 752
    Pkinase_Tyr; Protein tyrosine kinase

  3. XM_046944239.1 → XP_046800195.1  inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X2

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052580.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    27579936..27723385
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046922282.1 → XP_046778238.1  inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X3

  2. XM_046922284.1 → XP_046778240.1  inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X3

  3. XM_046922283.1 → XP_046778239.1  inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X3

  4. XM_046922285.1 → XP_046778241.1  inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X3

  5. XM_046922286.1 → XP_046778242.1  inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X3

  6. XM_046922280.1 → XP_046778236.1  inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X1

  7. XM_046922281.1 → XP_046778237.1  inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X2

Nucleotide Protein
Heading Accession and Version

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