U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PTPRU protein tyrosine phosphatase, receptor type U [ Gallus gallus (chicken) ]

Gene ID: 395153, updated on 3-Apr-2024

Summary

Symbol
PTPRUprovided by CGNC
Full Name
protein tyrosine phosphatase, receptor type Uprovided by CGNC
Primary source
CGNC:996
See related
Ensembl:ENSGALG00010016338
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
chromosome: 23
Exon count:
32
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 23 NC_052554.1 (3123559..3169696)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 23 NC_052595.1 (2890295..2936433)

Chromosome 23 - NC_052554.1Genomic Context describing neighboring genes Neighboring gene serine and arginine rich splicing factor 4 Neighboring gene mitochondrial trans-2-enoyl-CoA reductase Neighboring gene microRNA 1724 Neighboring gene uncharacterized LOC101748601 Neighboring gene uncharacterized LOC107055020 Neighboring gene uncharacterized LOC121107502

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
receptor-type tyrosine-protein phosphatase U
Names
R-PTP-U
R-PTP-psi
cRPTPPSI
phosphoprotein phosphatase
receptor tyrosine phosphatase
receptor-type protein-tyrosine phosphatase psi
NP_989823.1
XP_046759467.1
XP_046759468.1
XP_046759469.1
XP_046759470.1
XP_046759472.1
XP_046759473.1
XP_046759474.1
XP_046759475.1
XP_046759476.1
XP_046759477.1
XP_046787781.1
XP_046787782.1
XP_046787783.1
XP_046787784.1
XP_046787785.1
XP_046787786.1
XP_046787787.1
XP_046787788.1
XP_046787789.1
XP_046787790.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204492.2NP_989823.1  receptor-type tyrosine-protein phosphatase U precursor

    See identical proteins and their annotated locations for NP_989823.1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000339
    UniProtKB/Swiss-Prot
    Q6YI48, Q90948
    UniProtKB/TrEMBL
    A0A8V0YVA0
    Related
    ENSGALP00010022676.1, ENSGALT00010039315.1
    Conserved Domains (8) summary
    cd06263
    Location:27185
    MAM; Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members ...
    smart00194
    Location:11631426
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:195281
    IG_like; Immunoglobulin like
    cd00047
    Location:9131131
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:491584
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:290365
    fn3; Fibronectin type III domain
    pfam00102
    Location:9021131
    Y_phosphatase; Protein-tyrosine phosphatase
    pfam00629
    Location:27187
    MAM; MAM domain, meprin/A5/mu

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052554.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    3123559..3169696
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046903511.1XP_046759467.1  receptor-type tyrosine-protein phosphatase U isoform X1

  2. XM_046903513.1XP_046759469.1  receptor-type tyrosine-protein phosphatase U isoform X3

  3. XM_046903516.1XP_046759472.1  receptor-type tyrosine-protein phosphatase U isoform X5

  4. XM_046903518.1XP_046759474.1  receptor-type tyrosine-protein phosphatase U isoform X7

  5. XM_046903514.1XP_046759470.1  receptor-type tyrosine-protein phosphatase U isoform X4

  6. XM_046903517.1XP_046759473.1  receptor-type tyrosine-protein phosphatase U isoform X6

    Related
    ENSGALP00010022682.1, ENSGALT00010039323.1
  7. XM_046903520.1XP_046759476.1  receptor-type tyrosine-protein phosphatase U isoform X9

  8. XM_046903512.1XP_046759468.1  receptor-type tyrosine-protein phosphatase U isoform X2

    UniProtKB/TrEMBL
    A0A8V0YVP7
    Related
    ENSGALP00010022699.1, ENSGALT00010039343.1
  9. XM_046903519.1XP_046759475.1  receptor-type tyrosine-protein phosphatase U isoform X8

  10. XM_046903521.1XP_046759477.1  receptor-type tyrosine-protein phosphatase U isoform X10

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052595.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    2890295..2936433
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046931825.1XP_046787781.1  receptor-type tyrosine-protein phosphatase U isoform X1

  2. XM_046931827.1XP_046787783.1  receptor-type tyrosine-protein phosphatase U isoform X3

  3. XM_046931829.1XP_046787785.1  receptor-type tyrosine-protein phosphatase U isoform X5

  4. XM_046931831.1XP_046787787.1  receptor-type tyrosine-protein phosphatase U isoform X7

  5. XM_046931828.1XP_046787784.1  receptor-type tyrosine-protein phosphatase U isoform X4

  6. XM_046931830.1XP_046787786.1  receptor-type tyrosine-protein phosphatase U isoform X6

  7. XM_046931833.1XP_046787789.1  receptor-type tyrosine-protein phosphatase U isoform X9

  8. XM_046931826.1XP_046787782.1  receptor-type tyrosine-protein phosphatase U isoform X2

  9. XM_046931832.1XP_046787788.1  receptor-type tyrosine-protein phosphatase U isoform X8

  10. XM_046931834.1XP_046787790.1  receptor-type tyrosine-protein phosphatase U isoform X10