U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

TCF3 transcription factor 3 [ Gallus gallus (chicken) ]

Gene ID: 395146, updated on 3-Apr-2024

Summary

Symbol
TCF3provided by CGNC
Full Name
transcription factor 3provided by CGNC
Primary source
CGNC:739
See related
Ensembl:ENSGALG00010027700
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
G12
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
chromosome: 28
Exon count:
25
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 28 NC_052559.1 (2798549..2856277)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 28 NC_052600.1 (2364051..2422233)

Chromosome 28 - NC_052559.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121107746 Neighboring gene one cut homeobox 3 Neighboring gene uncharacterized LOC112530436 Neighboring gene ubiquinol-cytochrome c reductase, complex III subunit XI Neighboring gene uncharacterized LOC121107747 Neighboring gene methyl-CpG binding domain protein 3

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General protein information

Preferred Names
transcription factor E2-alpha
Names
class A basic helix-loop-helix transcription factor G12
helix-loop-helix protein E12
helix-loop-helix protein E47
transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204486.3NP_989817.2  transcription factor E2-alpha

    See identical proteins and their annotated locations for NP_989817.2

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000375
    UniProtKB/TrEMBL
    A0A8V1AFF8, F1NVL4, Q70IK3
    Related
    ENSGALP00010041050.1, ENSGALT00010067146.1
    Conserved Domains (2) summary
    smart00353
    Location:570623
    HLH; helix loop helix domain
    pfam11861
    Location:510577
    DUF3381; Domain of unknown function (DUF3381)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052559.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    2798549..2856277
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015299889.4XP_015155375.1  transcription factor E2-alpha isoform X1

    UniProtKB/TrEMBL
    A0A8V1A560
    Conserved Domains (2) summary
    smart00353
    Location:605658
    HLH; helix loop helix domain
    pfam11861
    Location:540612
    DUF3381; Domain of unknown function (DUF3381)
  2. XM_015299892.4XP_015155378.1  transcription factor E2-alpha isoform X4

    UniProtKB/TrEMBL
    A0A8V1A560
    Conserved Domains (1) summary
    smart00353
    Location:601654
    HLH; helix loop helix domain
  3. XM_015299895.4XP_015155381.1  transcription factor E2-alpha isoform X6

    UniProtKB/TrEMBL
    A0A8V1A560
    Conserved Domains (1) summary
    smart00353
    Location:600653
    HLH; helix loop helix domain
  4. XM_015299894.4XP_015155380.1  transcription factor E2-alpha isoform X5

    UniProtKB/TrEMBL
    A0A8V1AFF8
    Conserved Domains (2) summary
    smart00353
    Location:600653
    HLH; helix loop helix domain
    pfam11861
    Location:540607
    DUF3381; Domain of unknown function (DUF3381)
  5. XM_015299896.4XP_015155382.1  transcription factor E2-alpha isoform X9

    UniProtKB/TrEMBL
    A0A8V1A560
    Conserved Domains (1) summary
    smart00353
    Location:596649
    HLH; helix loop helix domain
  6. XM_015299897.4XP_015155383.1  transcription factor E2-alpha isoform X10

    UniProtKB/TrEMBL
    Q5ZL14
    Conserved Domains (1) summary
    smart00353
    Location:595648
    HLH; helix loop helix domain
  7. XM_015299900.4XP_015155386.1  transcription factor E2-alpha isoform X14

    UniProtKB/TrEMBL
    A0A8V1A560
    Conserved Domains (2) summary
    smart00353
    Location:575628
    HLH; helix loop helix domain
    pfam11861
    Location:510582
    DUF3381; Domain of unknown function (DUF3381)
  8. XM_040653465.2XP_040509399.1  transcription factor E2-alpha isoform X18

    UniProtKB/TrEMBL
    A0A8V1A560
    Conserved Domains (1) summary
    cd18943
    Location:557630
    bHLH_E-protein_E47-like; basic helix-loop-helix (bHLH) domain found in transcription factor E47 and similar proteins
  9. XM_015299905.4XP_015155391.1  transcription factor E2-alpha isoform X28

    UniProtKB/TrEMBL
    A0A8V1A560, F1NEE1, Q70IK2
    Conserved Domains (1) summary
    smart00353
    Location:566619
    HLH; helix loop helix domain
  10. XM_015299906.4XP_015155392.1  transcription factor E2-alpha isoform X30

    UniProtKB/TrEMBL
    Q5ZL14
    Conserved Domains (1) summary
    smart00353
    Location:565618
    HLH; helix loop helix domain
  11. XM_015299890.4XP_015155376.1  transcription factor E2-alpha isoform X2

    UniProtKB/TrEMBL
    A0A8V1A560
    Conserved Domains (2) summary
    smart00353
    Location:604657
    HLH; helix loop helix domain
    pfam11861
    Location:539611
    DUF3381; Domain of unknown function (DUF3381)
  12. XM_040653461.2XP_040509395.1  transcription factor E2-alpha isoform X7

    UniProtKB/TrEMBL
    A0A8V1AFF8
    Conserved Domains (2) summary
    TIGR01622
    Location:513618
    SF-CC1; splicing factor, CC1-like family
    cd18945
    Location:587671
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins
  13. XM_015299901.4XP_015155387.1  transcription factor E2-alpha isoform X15

    UniProtKB/TrEMBL
    A0A8V1A560
    Conserved Domains (2) summary
    smart00353
    Location:574627
    HLH; helix loop helix domain
    pfam11861
    Location:509581
    DUF3381; Domain of unknown function (DUF3381)
  14. XM_040653467.2XP_040509401.1  transcription factor E2-alpha isoform X20

    UniProtKB/TrEMBL
    A0A8V1A560
    Conserved Domains (1) summary
    cd18943
    Location:556629
    bHLH_E-protein_E47-like; basic helix-loop-helix (bHLH) domain found in transcription factor E47 and similar proteins
  15. XM_040653469.2XP_040509403.1  transcription factor E2-alpha isoform X22

    UniProtKB/TrEMBL
    A0A8V1A560
    Conserved Domains (1) summary
    cd18943
    Location:555628
    bHLH_E-protein_E47-like; basic helix-loop-helix (bHLH) domain found in transcription factor E47 and similar proteins
  16. XM_040653471.2XP_040509405.1  transcription factor E2-alpha isoform X24

    UniProtKB/TrEMBL
    A0A8V1AFF8
    Conserved Domains (2) summary
    TIGR01622
    Location:483588
    SF-CC1; splicing factor, CC1-like family
    cd18945
    Location:557641
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins
  17. XM_040653474.2XP_040509408.1  transcription factor E2-alpha isoform X29

    UniProtKB/TrEMBL
    A0A8V1A560
    Related
    ENSGALP00010041049.1, ENSGALT00010067145.1
    Conserved Domains (1) summary
    cd18943
    Location:551624
    bHLH_E-protein_E47-like; basic helix-loop-helix (bHLH) domain found in transcription factor E47 and similar proteins
  18. XM_040653475.2XP_040509409.1  transcription factor E2-alpha isoform X33

    UniProtKB/TrEMBL
    Q5ZL14
    Conserved Domains (1) summary
    cd18943
    Location:550623
    bHLH_E-protein_E47-like; basic helix-loop-helix (bHLH) domain found in transcription factor E47 and similar proteins
  19. XM_015299891.4XP_015155377.1  transcription factor E2-alpha isoform X3

    UniProtKB/TrEMBL
    A0A8V1A560
    Conserved Domains (2) summary
    smart00353
    Location:604657
    HLH; helix loop helix domain
    pfam11861
    Location:539611
    DUF3381; Domain of unknown function (DUF3381)
  20. XM_015299902.4XP_015155388.1  transcription factor E2-alpha isoform X16

    UniProtKB/TrEMBL
    A0A8V1A560
    Conserved Domains (2) summary
    smart00353
    Location:574627
    HLH; helix loop helix domain
    pfam11861
    Location:509581
    DUF3381; Domain of unknown function (DUF3381)
  21. XM_015299910.4XP_015155396.1  transcription factor E2-alpha isoform X25

    UniProtKB/TrEMBL
    A0A8V1AFF8
    Conserved Domains (2) summary
    smart00353
    Location:569622
    HLH; helix loop helix domain
    pfam11861
    Location:509576
    DUF3381; Domain of unknown function (DUF3381)
  22. XM_015299912.4XP_015155398.1  transcription factor E2-alpha isoform X31

    UniProtKB/TrEMBL
    A0A8V1A560
    Conserved Domains (1) summary
    smart00353
    Location:565618
    HLH; helix loop helix domain
  23. XM_040653476.2XP_040509410.1  transcription factor E2-alpha isoform X35

    UniProtKB/TrEMBL
    Q5ZL14
    Conserved Domains (1) summary
    cd18943
    Location:550623
    bHLH_E-protein_E47-like; basic helix-loop-helix (bHLH) domain found in transcription factor E47 and similar proteins
  24. XM_040653462.2XP_040509396.1  transcription factor E2-alpha isoform X8

    UniProtKB/TrEMBL
    A0A8V1AFF8
    Conserved Domains (2) summary
    TIGR01622
    Location:512617
    SF-CC1; splicing factor, CC1-like family
    cd18945
    Location:586670
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins
  25. XM_040653463.2XP_040509397.1  transcription factor E2-alpha isoform X11

    UniProtKB/TrEMBL
    Q5ZL14
    Conserved Domains (2) summary
    PHA03307
    Location:61366
    PHA03307; transcriptional regulator ICP4; Provisional
    cd18943
    Location:579652
    bHLH_E-protein_E47-like; basic helix-loop-helix (bHLH) domain found in transcription factor E47 and similar proteins
  26. XM_015299903.4XP_015155389.1  transcription factor E2-alpha isoform X17

    UniProtKB/TrEMBL
    A0A8V1A560
    Related
    ENSGALP00010041045.1, ENSGALT00010067141.1
    Conserved Domains (2) summary
    smart00353
    Location:573626
    HLH; helix loop helix domain
    pfam11861
    Location:508580
    DUF3381; Domain of unknown function (DUF3381)
  27. XM_040653470.2XP_040509404.1  transcription factor E2-alpha isoform X23

    UniProtKB/TrEMBL
    A0A8V1A560
    Conserved Domains (1) summary
    cd18943
    Location:555628
    bHLH_E-protein_E47-like; basic helix-loop-helix (bHLH) domain found in transcription factor E47 and similar proteins
  28. XM_040653472.2XP_040509406.1  transcription factor E2-alpha isoform X26

    UniProtKB/TrEMBL
    A0A8V1A560
    Conserved Domains (1) summary
    cd18943
    Location:554627
    bHLH_E-protein_E47-like; basic helix-loop-helix (bHLH) domain found in transcription factor E47 and similar proteins
  29. XM_015299911.4XP_015155397.1  transcription factor E2-alpha isoform X27

    UniProtKB/TrEMBL
    A0A8V1AFF8
    Conserved Domains (2) summary
    smart00353
    Location:568621
    HLH; helix loop helix domain
    pfam11861
    Location:508575
    DUF3381; Domain of unknown function (DUF3381)
  30. XM_015299913.4XP_015155399.1  transcription factor E2-alpha isoform X34

    UniProtKB/TrEMBL
    A0A8V1A560
    Conserved Domains (1) summary
    smart00353
    Location:564617
    HLH; helix loop helix domain
  31. XM_015299914.4XP_015155400.1  transcription factor E2-alpha isoform X37

    UniProtKB/TrEMBL
    Q5ZL14
    Conserved Domains (1) summary
    smart00353
    Location:563616
    HLH; helix loop helix domain
  32. XM_040653466.2XP_040509400.1  transcription factor E2-alpha isoform X19

    UniProtKB/TrEMBL
    A0A8V1A560
    Conserved Domains (1) summary
    cl00081
    Location:599657
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily
  33. XM_040653468.2XP_040509402.1  transcription factor E2-alpha isoform X21

    UniProtKB/TrEMBL
    A0A8V1A560
    Related
    ENSGALP00010041047.1, ENSGALT00010067143.1
    Conserved Domains (1) summary
    cl00081
    Location:599657
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily
  34. XM_015299909.4XP_015155395.1  transcription factor E2-alpha isoform X38

    UniProtKB/TrEMBL
    A0A8V1A560
    Conserved Domains (2) summary
    smart00353
    Location:605658
    HLH; helix loop helix domain
    pfam11861
    Location:540612
    DUF3381; Domain of unknown function (DUF3381)
  35. XM_046904524.1XP_046760480.1  transcription factor E2-alpha isoform X48

  36. XM_046904525.1XP_046760481.1  transcription factor E2-alpha isoform X48

  37. XM_015299907.4XP_015155393.1  transcription factor E2-alpha isoform X32

    UniProtKB/TrEMBL
    A0A8V1AA14
  38. XM_046904522.1XP_046760478.1  transcription factor E2-alpha isoform X41

  39. XM_046904523.1XP_046760479.1  transcription factor E2-alpha isoform X44

  40. XM_040653478.2XP_040509412.1  transcription factor E2-alpha isoform X39

    UniProtKB/TrEMBL
    A0A8V1AA14
    Related
    ENSGALP00010041041.1, ENSGALT00010067137.1
    Conserved Domains (1) summary
    cd18943
    Location:545618
    bHLH_E-protein_E47-like; basic helix-loop-helix (bHLH) domain found in transcription factor E47 and similar proteins
  41. XM_040653479.2XP_040509413.1  transcription factor E2-alpha isoform X42

    UniProtKB/TrEMBL
    A0A1D5PPL4
    Conserved Domains (2) summary
    TIGR01622
    Location:443548
    SF-CC1; splicing factor, CC1-like family
    cd18945
    Location:517601
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins
  42. XM_040653480.2XP_040509414.1  transcription factor E2-alpha isoform X43

    UniProtKB/TrEMBL
    A0A8V1AA14
    Conserved Domains (1) summary
    cd18943
    Location:511584
    bHLH_E-protein_E47-like; basic helix-loop-helix (bHLH) domain found in transcription factor E47 and similar proteins
  43. XM_040653481.2XP_040509415.1  transcription factor E2-alpha isoform X45

    UniProtKB/TrEMBL
    Q5ZL14
    Conserved Domains (1) summary
    cd18943
    Location:510583
    bHLH_E-protein_E47-like; basic helix-loop-helix (bHLH) domain found in transcription factor E47 and similar proteins
  44. XM_015299908.4XP_015155394.1  transcription factor E2-alpha isoform X36

    UniProtKB/TrEMBL
    A0A8V1AA14
    Conserved Domains (2) summary
    smart00353
    Location:564617
    HLH; helix loop helix domain
    pfam11861
    Location:499571
    DUF3381; Domain of unknown function (DUF3381)
  45. XM_046904521.1XP_046760477.1  transcription factor E2-alpha isoform X40

  46. XM_040653482.2XP_040509416.1  transcription factor E2-alpha isoform X46

    UniProtKB/TrEMBL
    A0A8V1AA14
    Conserved Domains (1) summary
    cd18943
    Location:510583
    bHLH_E-protein_E47-like; basic helix-loop-helix (bHLH) domain found in transcription factor E47 and similar proteins
  47. XM_040653483.2XP_040509417.1  transcription factor E2-alpha isoform X47

    UniProtKB/TrEMBL
    Q5ZL14
    Conserved Domains (1) summary
    cd18943
    Location:509582
    bHLH_E-protein_E47-like; basic helix-loop-helix (bHLH) domain found in transcription factor E47 and similar proteins
  48. XM_015299898.4XP_015155384.2  transcription factor E2-alpha isoform X12

  49. XM_015299899.4XP_015155385.2  transcription factor E2-alpha isoform X13

    Related
    ENSGALP00010041040.1, ENSGALT00010067136.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052600.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    2364051..2422233
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046933618.1XP_046789574.1  transcription factor E2-alpha isoform X1

  2. XM_046933621.1XP_046789577.1  transcription factor E2-alpha isoform X4

  3. XM_046933623.1XP_046789579.1  transcription factor E2-alpha isoform X6

  4. XM_046933622.1XP_046789578.1  transcription factor E2-alpha isoform X5

  5. XM_046933626.1XP_046789582.1  transcription factor E2-alpha isoform X9

  6. XM_046933627.1XP_046789583.1  transcription factor E2-alpha isoform X10

  7. XM_046933631.1XP_046789587.1  transcription factor E2-alpha isoform X14

  8. XM_046933635.1XP_046789591.1  transcription factor E2-alpha isoform X18

  9. XM_046933645.1XP_046789601.1  transcription factor E2-alpha isoform X28

    UniProtKB/TrEMBL
    F1NEE1, Q70IK2
  10. XM_046933647.1XP_046789603.1  transcription factor E2-alpha isoform X30

  11. XM_046933619.1XP_046789575.1  transcription factor E2-alpha isoform X2

  12. XM_046933624.1XP_046789580.1  transcription factor E2-alpha isoform X7

  13. XM_046933632.1XP_046789588.1  transcription factor E2-alpha isoform X15

  14. XM_046933637.1XP_046789593.1  transcription factor E2-alpha isoform X20

  15. XM_046933639.1XP_046789595.1  transcription factor E2-alpha isoform X22

  16. XM_046933641.1XP_046789597.1  transcription factor E2-alpha isoform X24

  17. XM_046933646.1XP_046789602.1  transcription factor E2-alpha isoform X29

  18. XM_046933650.1XP_046789606.1  transcription factor E2-alpha isoform X33

  19. XM_046933620.1XP_046789576.1  transcription factor E2-alpha isoform X3

  20. XM_046933633.1XP_046789589.1  transcription factor E2-alpha isoform X16

  21. XM_046933642.1XP_046789598.1  transcription factor E2-alpha isoform X25

  22. XM_046933648.1XP_046789604.1  transcription factor E2-alpha isoform X31

  23. XM_046933652.1XP_046789608.1  transcription factor E2-alpha isoform X35

  24. XM_046933625.1XP_046789581.1  transcription factor E2-alpha isoform X8

  25. XM_046933628.1XP_046789584.1  transcription factor E2-alpha isoform X11

  26. XM_046933634.1XP_046789590.1  transcription factor E2-alpha isoform X17

  27. XM_046933640.1XP_046789596.1  transcription factor E2-alpha isoform X23

  28. XM_046933643.1XP_046789599.1  transcription factor E2-alpha isoform X26

  29. XM_046933644.1XP_046789600.1  transcription factor E2-alpha isoform X27

  30. XM_046933651.1XP_046789607.1  transcription factor E2-alpha isoform X34

  31. XM_046933654.1XP_046789610.1  transcription factor E2-alpha isoform X37

  32. XM_046933636.1XP_046789592.1  transcription factor E2-alpha isoform X19

  33. XM_046933638.1XP_046789594.1  transcription factor E2-alpha isoform X21

  34. XM_046933655.1XP_046789611.1  transcription factor E2-alpha isoform X38

  35. XM_046933666.1XP_046789622.1  transcription factor E2-alpha isoform X48

  36. XM_046933667.1XP_046789623.1  transcription factor E2-alpha isoform X48

  37. XM_046933649.1XP_046789605.1  transcription factor E2-alpha isoform X32

  38. XM_046933658.1XP_046789614.1  transcription factor E2-alpha isoform X41

  39. XM_046933662.1XP_046789618.1  transcription factor E2-alpha isoform X44

  40. XM_046933656.1XP_046789612.1  transcription factor E2-alpha isoform X39

  41. XM_046933659.1XP_046789615.1  transcription factor E2-alpha isoform X42

  42. XM_046933660.1XP_046789616.1  transcription factor E2-alpha isoform X43

  43. XM_046933663.1XP_046789619.1  transcription factor E2-alpha isoform X45

  44. XM_046933653.1XP_046789609.1  transcription factor E2-alpha isoform X36

  45. XM_046933657.1XP_046789613.1  transcription factor E2-alpha isoform X40

  46. XM_046933664.1XP_046789620.1  transcription factor E2-alpha isoform X46

  47. XM_046933665.1XP_046789621.1  transcription factor E2-alpha isoform X47

  48. XM_046933629.1XP_046789585.1  transcription factor E2-alpha isoform X12

  49. XM_046933630.1XP_046789586.1  transcription factor E2-alpha isoform X13