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PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme [ Gallus gallus (chicken) ]

Gene ID: 395113, updated on 3-Apr-2024

Summary

Symbol
PPP3CAprovided by CGNC
Full Name
protein phosphatase 3, catalytic subunit, alpha isozymeprovided by CGNC
Primary source
CGNC:9327
See related
Ensembl:ENSGALG00010005416
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
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Genomic context

Location:
chromosome: 4
Exon count:
18
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (59813643..60009655, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (59816046..60006909, complement)

Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110725 Neighboring gene endomucin Neighboring gene B-cell scaffold protein with ankyrin repeats 1 Neighboring gene uncharacterized LOC121110727 Neighboring gene solute carrier family 39 member 8

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables calmodulin-dependent protein phosphatase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in calcineurin-NFAT signaling cascade IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of calcineurin complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
Names
calcineurin A alpha
XP_015141104.1
XP_015141105.1
XP_015141106.1
XP_015141107.1
XP_015141108.1
XP_015141109.1
XP_040527127.1
XP_040527128.1
XP_040527131.1
XP_040527132.1
XP_040527133.1
XP_040527134.1
XP_040527135.1
XP_040555814.1
XP_046773057.1
XP_046773058.1
XP_046773059.1
XP_046773060.1
XP_046773061.1
XP_046773062.1
XP_046796805.1
XP_046796806.1
XP_046796807.1
XP_046796808.1
XP_046796809.1
XP_046796810.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    59813643..60009655 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015285623.4XP_015141109.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X6

    UniProtKB/TrEMBL
    Q7T1F5
    Related
    ENSGALP00010007461.1, ENSGALT00010012899.1
    Conserved Domains (1) summary
    cd07416
    Location:41345
    MPP_PP2B; PP2B, metallophosphatase domain
  2. XM_015285620.4XP_015141106.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X3

    UniProtKB/TrEMBL
    Q7T1F5
    Conserved Domains (1) summary
    cd07416
    Location:41345
    MPP_PP2B; PP2B, metallophosphatase domain
  3. XM_015285622.4XP_015141108.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X5

    UniProtKB/TrEMBL
    Q7T1F5
    Conserved Domains (1) summary
    cd07416
    Location:41345
    MPP_PP2B; PP2B, metallophosphatase domain
  4. XM_015285619.4XP_015141105.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X2

    UniProtKB/TrEMBL
    Q7T1F5
    Conserved Domains (1) summary
    cd07416
    Location:41345
    MPP_PP2B; PP2B, metallophosphatase domain
  5. XM_015285621.4XP_015141107.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X4

    UniProtKB/TrEMBL
    A0A8V0XL95, Q7T1F5
    Related
    ENSGALP00010007466.1, ENSGALT00010012904.1
    Conserved Domains (1) summary
    cd07416
    Location:41345
    MPP_PP2B; PP2B, metallophosphatase domain
  6. XM_015285618.4XP_015141104.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1

    UniProtKB/TrEMBL
    A0A8V0XRD8, Q7T1F5
    Related
    ENSGALP00010007465.1, ENSGALT00010012903.1
    Conserved Domains (1) summary
    cd07416
    Location:41345
    MPP_PP2B; PP2B, metallophosphatase domain
  7. XM_046940853.1XP_046796809.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X8

  8. XM_046940850.1XP_046796806.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X7

  9. XM_046940849.1XP_046796805.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X7

  10. XM_046940851.1XP_046796807.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X7

  11. XM_046940854.1XP_046796810.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X9

  12. XM_040699880.2XP_040555814.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X7

    UniProtKB/TrEMBL
    Q7T1F5
    Conserved Domains (1) summary
    cd07416
    Location:1295
    MPP_PP2B; PP2B, metallophosphatase domain
  13. XM_046940852.1XP_046796808.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X7

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    59816046..60006909 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040671200.2XP_040527134.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X6

    UniProtKB/TrEMBL
    Q7T1F5
    Conserved Domains (1) summary
    cd07416
    Location:41345
    MPP_PP2B; PP2B, metallophosphatase domain
  2. XM_040671197.2XP_040527131.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X3

    UniProtKB/TrEMBL
    Q7T1F5
    Conserved Domains (1) summary
    cd07416
    Location:41345
    MPP_PP2B; PP2B, metallophosphatase domain
  3. XM_040671199.2XP_040527133.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X5

    UniProtKB/TrEMBL
    Q7T1F5
    Conserved Domains (1) summary
    cd07416
    Location:41345
    MPP_PP2B; PP2B, metallophosphatase domain
  4. XM_040671194.2XP_040527128.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X2

    UniProtKB/TrEMBL
    Q7T1F5
    Conserved Domains (1) summary
    cd07416
    Location:41345
    MPP_PP2B; PP2B, metallophosphatase domain
  5. XM_040671198.2XP_040527132.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X4

    UniProtKB/TrEMBL
    A0A8V0XL95, Q7T1F5
    Conserved Domains (1) summary
    cd07416
    Location:41345
    MPP_PP2B; PP2B, metallophosphatase domain
  6. XM_040671193.2XP_040527127.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1

    UniProtKB/TrEMBL
    A0A8V0XRD8, Q7T1F5
    Conserved Domains (1) summary
    cd07416
    Location:41345
    MPP_PP2B; PP2B, metallophosphatase domain
  7. XM_046917105.1XP_046773061.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X8

  8. XM_046917102.1XP_046773058.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X7

  9. XM_046917101.1XP_046773057.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X7

  10. XM_046917103.1XP_046773059.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X7

  11. XM_046917106.1XP_046773062.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X9

  12. XM_040671201.2XP_040527135.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X7

    UniProtKB/TrEMBL
    Q7T1F5
    Conserved Domains (1) summary
    cd07416
    Location:1295
    MPP_PP2B; PP2B, metallophosphatase domain
  13. XM_046917104.1XP_046773060.1  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X7