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Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 [ Mus musculus (house mouse) ]

Gene ID: 394430, updated on 8-Feb-2024

Summary

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Official Symbol
Ugt1a10provided by MGI
Official Full Name
UDP glycosyltransferase 1 family, polypeptide A10provided by MGI
Primary source
MGI:MGI:3580642
See related
Ensembl:ENSMUSG00000090165 AllianceGenome:MGI:3580642
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A13; Ugt1a13
Summary
Predicted to enable several functions, including fatty acid binding activity; protein dimerization activity; and protein kinase C binding activity. Predicted to be involved in flavonoid glucuronidation and xenobiotic glucuronidation. Predicted to be located in endoplasmic reticulum. Is expressed in several structures, including alimentary system; integumental system; metanephros; nervous system; and nose. Human ortholog(s) of this gene implicated in alcoholic pancreatitis and pancreatic cancer. Orthologous to several human genes including UGT1A10 (UDP glucuronosyltransferase family 1 member A10); UGT1A7 (UDP glucuronosyltransferase family 1 member A7); and UGT1A8 (UDP glucuronosyltransferase family 1 member A8). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in kidney adult (RPKM 238.9), liver adult (RPKM 145.6) and 8 other tissues See more
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Genomic context

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Location:
1 D; 1 44.49 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (87983133..88147724)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (88055411..88220002)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene UDP glycosyltransferase 1 family, polypeptide A10 pseudogene Neighboring gene karyopherin (importin) alpha 2 pseudogene Neighboring gene predicted gene, 38421 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A9 Neighboring gene STARR-seq mESC enhancer starr_01626 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A8 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A7C Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A6B Neighboring gene STARR-seq mESC enhancer starr_01627 Neighboring gene STARR-seq mESC enhancer starr_01628 Neighboring gene predicted gene 15372 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A6A Neighboring gene UDP glycosyltransferase 1 family, polypeptide A10 pseudogene Neighboring gene predicted gene 15371 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A5 Neighboring gene predicted gene 15368 Neighboring gene STARR-positive B cell enhancer mm9_chr1:90112870-90113171 Neighboring gene predicted gene 15376 Neighboring gene STARR-positive B cell enhancer mm9_chr1:90113610-90113910 Neighboring gene STARR-seq mESC enhancer starr_01629 Neighboring gene STARR-positive B cell enhancer mm9_chr1:90118277-90118578 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A2 Neighboring gene DnaJ heat shock protein family (Hsp40) member B3 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A1 Neighboring gene maestro heat-like repeat family member 2A Neighboring gene STARR-positive B cell enhancer mm9_chr1:90185502-90185802 Neighboring gene STARR-positive B cell enhancer mm9_chr1:90186563-90186863 Neighboring gene Holliday junction recognition protein Neighboring gene STARR-positive B cell enhancer mm9_chr1:90195708-90196009 Neighboring gene transient receptor potential cation channel, subfamily M, member 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation. Zhang T, et al. Genome Res, 2004 Jan. PMID 14672974, Free PMC Article
  2. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC107546

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
  
enables enzyme inhibitor activity ISO
Inferred from Sequence Orthology
more info
  
enables fatty acid binding ISO
Inferred from Sequence Orthology
more info
  
enables glucuronosyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
  
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
  
enables protein kinase C binding ISO
Inferred from Sequence Orthology
more info
  
enables steroid binding ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
UDP glycosyltransferase 1 family, polypeptide A10
Names
UDP glycosyltransferase 1 family polypeptide A13
NP_964003.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201641.2 → NP_964003.2  UDP glycosyltransferase 1 family, polypeptide A10 precursor

    Status: VALIDATED

    Source sequence(s)
    AC087780, AY227201, BC089569
    Consensus CDS
    CCDS35657.1
    UniProtKB/TrEMBL
    E9PXN7, Q5FW80
    Related
    ENSMUSP00000108767.4, ENSMUST00000113142.10
    Conserved Domains (2) summary
    PHA03392
    Location:14 → 502
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:26 → 521
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    87983133..88147724
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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