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ncoa4 nuclear receptor coactivator 4 [ Danio rerio (zebrafish) ]

Gene ID: 394104, updated on 27-Mar-2024

Summary

Official Symbol
ncoa4provided by ZNC
Official Full Name
nuclear receptor coactivator 4provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-689
See related
Ensembl:ENSDARG00000021439 AllianceGenome:ZFIN:ZDB-GENE-040426-689
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:55307; zgc:77270
Summary
Predicted to enable transcription coactivator activity. Acts upstream of or within erythrocyte differentiation. Is expressed in digestive system and hematopoietic system. Orthologous to human NCOA4 (nuclear receptor coactivator 4). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See ncoa4 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (3915260..3936555, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (3784664..3805959, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 135-like Neighboring gene translocase of inner mitochondrial membrane 23 homolog b (yeast) Neighboring gene uncharacterized LOC108192009 Neighboring gene Yip1 domain family, member 3 Neighboring gene leucine rich repeat containing 73

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Clone Names

  • MGC55307

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within erythrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within intracellular iron ion homeostasis IEA
Inferred from Electronic Annotation
more info
 
involved_in response to hormone IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
nuclear receptor coactivator 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201129.1NP_957423.1  nuclear receptor coactivator 4

    See identical proteins and their annotated locations for NP_957423.1

    Status: PROVISIONAL

    Source sequence(s)
    BC047166
    UniProtKB/TrEMBL
    Q802X2
    Related
    ENSDARP00000013664.7, ENSDART00000017052.9
    Conserved Domains (1) summary
    pfam12489
    Location:33161
    ARA70; Nuclear coactivator

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    3915260..3936555 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005156494.4XP_005156551.1  nuclear receptor coactivator 4 isoform X1

    See identical proteins and their annotated locations for XP_005156551.1

    UniProtKB/TrEMBL
    A0A8M2B394, Q6P0F7
    Conserved Domains (1) summary
    pfam12489
    Location:33161
    ARA70; Nuclear coactivator