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slc25a20 solute carrier family 25 member 20 [ Danio rerio (zebrafish) ]

Gene ID: 393833, updated on 27-Mar-2024

Summary

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Official Symbol
slc25a20provided by ZNC
Official Full Name
solute carrier family 25 member 20provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1869
See related
Ensembl:ENSDARG00000040401 AllianceGenome:ZFIN:ZDB-GENE-040426-1869
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:77760
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in visceral fat. Human ortholog(s) of this gene implicated in carnitine-acylcarnitine translocase deficiency. Orthologous to human SLC25A20 (solute carrier family 25 member 20). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 22
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (105376..109686)
105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (132347..136657)

Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene zgc:112334 Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor Neighboring gene protein kinase, cAMP-dependent, regulatory, type II, alpha, B Neighboring gene si:ch1073-335m2.2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Genetic deletion of gpr27 alters acylcarnitine metabolism, insulin sensitivity, and glucose homeostasis in zebrafish. Nath AK, et al. FASEB J, 2020 Jan. PMID 31914600, Free PMC Article
  2. Fatty Acid Oxidation in Zebrafish Adipose Tissue Is Promoted by 1α,25(OH)(2)D(3). Peng X, et al. Cell Rep, 2017 May 16. PMID 28514663
  3. Stimulation of glycolysis promotes cardiomyocyte proliferation after injury in adult zebrafish. Fukuda R, et al. EMBO Rep, 2020 Aug 5. PMID 32648304, Free PMC Article
  4. Targeted Gene Expression in Zebrafish Exposed to Chlorpyrifos-Oxon Confirms Phenotype-Specific Mechanisms Leading to Adverse Outcomes. Garcia-Reyero N, et al. Bull Environ Contam Toxicol, 2016 Jun. PMID 27086301, Free PMC Article
  5. Expression and regulation of drug transporters in vertebrate neutrophils. Foulkes MJ, et al. Sci Rep, 2017 Jul 10. PMID 28694436, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC77760

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables acyl carnitine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carnitine transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrial envelope IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
mitochondrial carnitine/acylcarnitine carrier protein
Names
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
NP_957153.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200859.1 → NP_957153.1  mitochondrial carnitine/acylcarnitine carrier protein

    See identical proteins and their annotated locations for NP_957153.1

    Status: PROVISIONAL

    Source sequence(s)
    BC062851
    UniProtKB/TrEMBL
    A0A8M1PDJ8, Q6P5K6
    Related
    ENSDARP00000059139.6, ENSDART00000059140.8
    Conserved Domains (2) summary
    PTZ00169
    Location:10 → 276
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    pfam00153
    Location:107 → 197
    Mito_carr; Mitochondrial carrier protein

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007133.7 Reference GRCz11 Primary Assembly

    Range
    105376..109686
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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