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rpl8 ribosomal protein L8 [ Danio rerio (zebrafish) ]

Gene ID: 393686, updated on 27-Mar-2024

Summary

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Official Symbol
rpl8provided by ZNC
Official Full Name
ribosomal protein L8provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1670
See related
Ensembl:ENSDARG00000014867 AllianceGenome:ZFIN:ZDB-GENE-040426-1670
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:73105; zgc:77641
Summary
Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to act upstream of or within translation. Predicted to be located in cytoplasm and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is expressed in endodermal cell; intestine; liver; and pancreas. Orthologous to human RPL8 (ribosomal protein L8). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (33323104..33329695, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (33512358..33518949, complement)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene lectin Neighboring gene ubiquitin specific peptidase 9 Neighboring gene DEAD-box helicase 3 X-linked a Neighboring gene nyctalopin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. TiO(2) nanoparticles and BPA are combined to impair the development of offspring zebrafish after parental coexposure. Chen L, et al. Chemosphere, 2019 Feb. PMID 30448753
  2. Activation of aryl hydrocarbon receptor by dioxin directly shifts gut microbiota in zebrafish. Sun Y, et al. Environ Pollut, 2019 Dec. PMID 31671369
  3. Tebuconazole induced oxidative stress related hepatotoxicity in adult and larval zebrafish (Danio rerio). Li S, et al. Chemosphere, 2020 Feb. PMID 31683439
  4. Extracellular Vesicles Released by Colorectal Cancer Cell Lines Modulate Innate Immune Response in Zebrafish Model: The Possible Role of Human Endogenous Retroviruses. Ferrari L, et al. Int J Mol Sci, 2019 Jul 26. PMID 31357477, Free PMC Article
  5. Chronic exposure to environmental levels of cis-bifenthrin: Enantioselectivity and reproductive effects on zebrafish (Danio rerio). Xiang D, et al. Environ Pollut, 2019 Aug. PMID 31078089

See all (86) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC73105

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of large ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein uL2; 60S ribosomal protein L8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200713.1 → NP_957007.1  large ribosomal subunit protein uL2

    See identical proteins and their annotated locations for NP_957007.1

    Status: PROVISIONAL

    Source sequence(s)
    BC059473
    UniProtKB/Swiss-Prot
    Q6P0V6
    Related
    ENSDARP00000115147.1, ENSDART00000140039.3
    Conserved Domains (1) summary
    cl40667
    Location:1 → 252
    RplB; Ribosomal protein L2 [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    33323104..33329695 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005167684.1 → XP_005167741.1  60S ribosomal protein L8 isoform X1

    See identical proteins and their annotated locations for XP_005167741.1

    UniProtKB/Swiss-Prot
    Q6P0V6
    Conserved Domains (1) summary
    cl40667
    Location:1 → 252
    RplB; Ribosomal protein L2 [Translation, ribosomal structure and biogenesis]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6P0V6.3 GenPept UniProtKB/Swiss-Prot:Q6P0V6

Gene LinkOut

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