ggt1a gamma-glutamyltransferase 1a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ggt1aprovided by ZNC
Official Full Name: gamma-glutamyltransferase 1aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1388
See related: Ensembl:ENSDARG00000023526 AllianceGenome:ZFIN:ZDB-GENE-040426-1388
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ggt1; zgc:64172
Summary: Predicted to enable glutathione hydrolase activity and peptidyltransferase activity. Predicted to be involved in several processes, including peptide metabolic process; response to estradiol; and response to tumor necrosis factor. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in lens and solid lens vesicle. Human ortholog(s) of this gene implicated in gamma-glutamyl transpeptidase deficiency. Orthologous to human GGT1 (gamma-glutamyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 8

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (40041828..40075983, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (40008716..40042209, complement)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glutathione hydrolase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glutathione hydrolase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables leukotriene C4 gamma-glutamyl transferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in glutathione catabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within glutathione catabolic process	IEA Inferred from Electronic Annotation more info
involved_in peptide modification	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of immune system process	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of inflammatory response	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: gamma-glutamyltransferase 1a; gamma-glutamyltranspeptidase 1

Names: gamma-glutamyltransferase 1

NP_956709.1

EC 2.3.2.2

XP_017212782.1

EC 2.3.2.2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.