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zgc:55558 zgc:55558 [ Danio rerio (zebrafish) ]

Gene ID: 393228, updated on 27-Mar-2024

Summary

Official Symbol
zgc:55558provided by ZNC
Official Full Name
zgc:55558provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-740
See related
Ensembl:ENSDARG00000013161 AllianceGenome:ZFIN:ZDB-GENE-040426-740
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in Ras protein signal transduction. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in brain; heart; liver; pleuroperitoneal region; and trunk musculature. Orthologous to human ERAS (ES cell expressed Ras). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 3
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (16664261..16679971)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (16514461..16530171)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 6 member 16a Neighboring gene solute carrier family 17 member 7a Neighboring gene polymerase (DNA directed), delta 1, catalytic subunit Neighboring gene glycogen synthase 1 (muscle)

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Clone Names

  • MGC55558

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GDP binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200258.1NP_956552.1  GTPase KRas

    See identical proteins and their annotated locations for NP_956552.1

    Status: PROVISIONAL

    Source sequence(s)
    BC048875
    UniProtKB/TrEMBL
    A0A2R8QFC2, A0A2R8QIQ6, Q7ZUL8
    Related
    ENSDARP00000022638.7, ENSDART00000013816.8
    Conserved Domains (2) summary
    cd04138
    Location:3164
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B
    smart00173
    Location:16166
    RAS; Ras subfamily of RAS small GTPases

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    16664261..16679971
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394525.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    298784..314494
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)