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TfIIEalpha Transcription factor IIEalpha [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39313, updated on 4-Apr-2024

Summary

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Official Symbol
TfIIEalphaprovided by FlyBase
Official Full Name
Transcription factor IIEalphaprovided by FlyBase
Primary source
FLYBASE:FBgn0015828
Locus tag
Dmel_CG10415
See related
AllianceGenome:FB:FBgn0015828
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG10415; Dmel\CG10415; dTFIIE-L; dTFIIEL; TfIIE; TFIIE; TFIIE-L; TfIIEa; TFIIEalpha
Summary
Involved in mRNA transcription by RNA polymerase II. Located in nucleus. Part of transcription factor TFIIE complex. Is expressed in organism. Orthologous to human GTF2E1 (general transcription factor IIE subunit 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See TfIIEalpha in Genome Data Viewer
Location:
68D2-68D2; 3-36 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11682038..11683805)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11675138..11676905)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45882 Neighboring gene long non-coding RNA:CR45884 Neighboring gene antisense RNA:CR45885 Neighboring gene Sugar baby Neighboring gene Pallidin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila TFIIE: purification, cloning, and functional reconstitution. Wang X, et al. Proc Natl Acad Sci U S A, 1997 Jan 21. PMID 9012800, Free PMC Article
  2. Control of transcription by Krüppel through interactions with TFIIB and TFIIE beta. Sauer F, et al. Nature, 1995 May 11. PMID 7753175
  3. Purification of the Drosophila RNA polymerase II general transcription factors. Austin RJ, et al. Proc Natl Acad Sci U S A, 1996 Jun 11. PMID 8650170, Free PMC Article
  4. Fractionation of the general RNA polymerase II transcription factors from Drosophila embryos. Wampler SL, et al. J Biol Chem, 1990 Dec 5. PMID 2250021
  5. DNA template and activator-coactivator requirements for transcriptional synergism by Drosophila bicoid. Sauer F, et al. Science, 1995 Dec 15. PMID 8525377

See all (49) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in mRNA transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in transcription initiation at RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
  
involved_in transcription initiation at RNA polymerase II promoter ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in transcription open complex formation at RNA polymerase II promoter IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
part_of transcription factor TFIIE complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription factor TFIIE complex IPI
Inferred from Physical Interaction
more info
 PubMed 
part_of transcription factor TFIIE complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
transcription factor IIEalpha
Names
CG10415-PA
TfIIEalpha-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    11682038..11683805
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079302.4 → NP_524026.1  transcription factor IIEalpha [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524026.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O96880
    Related
    FBpp0075839
    Conserved Domains (3) summary
    smart00531
    Location:43 → 188
    TFIIE; Transcription initiation factor IIE
    pfam11521
    Location:357 → 429
    TFIIE-A_C; C-terminal general transcription factor TFIIE alpha
    cl21459
    Location:30 → 137
    HTH; Helix-turn-helix domains
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O96880 O96880

Gene LinkOut

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