CSNK1E casein kinase 1 epsilon [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: CSNK1Eprovided by CGNC
Official Full Name: casein kinase 1 epsilonprovided by CGNC
Primary source: CGNC:13829
See related: Ensembl:ENSGALG00010012911
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: DBT
Summary: The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. [provided by RefSeq, Feb 2014]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	1	NC_052532.1 (50967353..50989271)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	1	NC_052573.1 (51264899..51286818)

Chromosome 1 - NC_052532.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in endocytosis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in peptidyl-serine phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: casein kinase I isoform epsilon; casein kinase I

Names: CKI-epsilon; CKIe

NP_989708.3

EC 2.7.11.1

XP_046754244.1

EC 2.7.11.1

XP_046754256.1

EC 2.7.11.1

XP_046754279.1

EC 2.7.11.1

XP_046754299.1

EC 2.7.11.1

XP_046762398.1

EC 2.7.11.1

XP_046762399.1

EC 2.7.11.1

XP_046762400.1

EC 2.7.11.1

XP_046762401.1

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_204377.4 → NP_989708.3 casein kinase I isoform epsilon

See identical proteins and their annotated locations for NP_989708.3

Status: VALIDATED

Source sequence(s)

JAENSK010000012

UniProtKB/Swiss-Prot

Q5ZLL1, Q7T1G2, Q7T3L8

UniProtKB/TrEMBL

A0A8V0YJI7

Related

ENSGALP00010018005.1, ENSGALT00010030985.1

Conserved Domains (1) summary

cd14125
Location:8 → 282

STKc_CK1_delta_epsilon; Catalytic domain of the Serine/Threonine protein kinases, Casein Kinase 1 delta and epsilon