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Polr3K RNA polymerase III subunit K [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3772344, updated on 29-Dec-2023

Summary

Official Symbol
Polr3Kprovided by FlyBase
Official Full Name
RNA polymerase III subunit Kprovided by FlyBase
Primary source
FLYBASE:FBgn0061362
Locus tag
Dmel_CG33785
See related
AllianceGenome:FB:FBgn0061362
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG10438; CG10438a; CG30144; CG33005; CG33005-ORFA; CG33005ORFA; CG33785; Dmel\CG33785; Dromel_CG33786_FBtr0091786_uORF; RPC11
Summary
Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to contribute to RNA polymerase III activity. Predicted to be involved in tRNA transcription by RNA polymerase III and termination of RNA polymerase III transcription. Predicted to be part of RNA polymerase III complex. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human POLR3K (RNA polymerase III subunit K). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See Polr3K in Genome Data Viewer
Location:
57A8-57A9; 2-91 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20642466..20643785, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16529971..16531290, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene rigor mortis Neighboring gene uncharacterized protein Neighboring gene maf-S Neighboring gene uncharacterized protein Neighboring gene Threonyl-carbamoyl synthesis 1 Neighboring gene DNA methyltransferase 1 associated protein 1 Neighboring gene Leucine-rich tendon-specific protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA-directed 5'-3' RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 
contributes_to RNA polymerase III activity IBA
Inferred from Biological aspect of Ancestor
more info
 
contributes_to RNA polymerase III activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
involved_in tRNA transcription by RNA polymerase III ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in termination of RNA polymerase III transcription IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of RNA polymerase III complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of RNA polymerase III complex ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
RNA polymerase III subunit K
Names
CG33785-PA
Polr3K-PA
NP_001027443.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    20642466..20643785 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001032272.4NP_001027443.1  RNA polymerase III subunit K [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001027443.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1ZBX4, C3KGN0
    Conserved Domains (1) summary
    COG1594
    Location:1108
    RPB9; DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS [Transcription]