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PTCH2 patched 2 [ Gallus gallus (chicken) ]

Gene ID: 374187, updated on 5-Mar-2024

Summary

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Symbol
PTCH2provided by CGNC
Full Name
patched 2provided by CGNC
Primary source
CGNC:14936
See related
Ensembl:ENSGALG00010025862
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
24
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 8 NC_052539.1 (20485292..20502139, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 8 NC_052580.1 (20494601..20511431, complement)

Chromosome 8 - NC_052539.1Genomic Context describing neighboring genes Neighboring gene Tctex1 domain containing 4 Neighboring gene polo like kinase 3 Neighboring gene BTB domain containing 19 Neighboring gene eukaryotic translation initiation factor 2B subunit gamma Neighboring gene HECT domain E3 ubiquitin protein ligase 3 like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ptc1 and Ptc2 transcripts provide distinct readouts of Hedgehog signaling activity during chick embryogenesis. Pearse RV 2nd, et al. Dev Biol, 2001 Nov 1. PMID 11784016

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hedgehog family protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hedgehog receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables smoothened binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in smoothened signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein patched homolog 2
Names
patched homolog 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052539.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    20485292..20502139 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025153073.3 → XP_025008841.1  protein patched homolog 2 isoform X2

    UniProtKB/TrEMBL
    A0A8V1A4E2
    Related
    ENSGALP00010038914.1, ENSGALT00010063035.1
    Conserved Domains (2) summary
    PHA03247
    Location:1210 → 1369
    PHA03247; large tegument protein UL36; Provisional
    cl25655
    Location:103 → 1231
    Patched; Patched family

  2. XM_025153072.3 → XP_025008840.1  protein patched homolog 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V1A4E2
    Conserved Domains (2) summary
    PHA03247
    Location:1236 → 1395
    PHA03247; large tegument protein UL36; Provisional
    cl25655
    Location:129 → 1257
    Patched; Patched family

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052580.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    20494601..20511431 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040678413.2 → XP_040534347.1  protein patched homolog 2 isoform X2

    UniProtKB/TrEMBL
    A0A8V1A4E2
    Conserved Domains (2) summary
    PHA03247
    Location:1210 → 1369
    PHA03247; large tegument protein UL36; Provisional
    cl25655
    Location:103 → 1231
    Patched; Patched family

  2. XM_040678412.2 → XP_040534346.1  protein patched homolog 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V1A4E2
    Conserved Domains (2) summary
    PHA03247
    Location:1236 → 1395
    PHA03247; large tegument protein UL36; Provisional
    cl25655
    Location:129 → 1257
    Patched; Patched family
Nucleotide Protein
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