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ROCK2 Rho associated coiled-coil containing protein kinase 2 [ Gallus gallus (chicken) ]

Gene ID: 374182, updated on 5-Mar-2024

Summary

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Symbol
ROCK2provided by CGNC
Full Name
Rho associated coiled-coil containing protein kinase 2provided by CGNC
Primary source
CGNC:12317
See related
Ensembl:ENSGALG00010002706
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
34
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (96866718..96961314, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (96681924..96776486, complement)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene chromosome 2 open reading frame 50 Neighboring gene PQ loop repeat containing 3 Neighboring gene uncharacterized LOC121110481 Neighboring gene E2F transcription factor 6 Neighboring gene growth regulating estrogen receptor binding 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. RHOA-ROCK signalling is necessary for lateralization and differentiation of the developing sinoatrial node. Vicente-Steijn R, et al. Cardiovasc Res, 2017 Aug 1. PMID 28899000
  2. Rho kinases play an obligatory role in vertebrate embryonic organogenesis. Wei L, et al. Development, 2001 Aug. PMID 11532918

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables Rho-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in actomyosin structure organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cortical actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in embryonic morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic cytokinesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-threonine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of centrosome duplication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell junction assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in smooth muscle contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho-associated protein kinase 2
XP_015131571.3
XP_015131572.3
XP_015131573.3
XP_025005180.3
XP_040524785.2
XP_040524786.2
XP_040524787.2
XP_040524788.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    96866718..96961314 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025149412.3 → XP_025005180.3  rho-associated protein kinase 2 isoform X4

    Related
    ENSGALP00010003887.1, ENSGALT00010006275.1

  2. XM_015276087.4 → XP_015131573.3  rho-associated protein kinase 2 isoform X3

  3. XM_015276086.4 → XP_015131572.3  rho-associated protein kinase 2 isoform X2

    Related
    ENSGALP00010003891.1, ENSGALT00010006284.1

  4. XM_015276085.4 → XP_015131571.3  rho-associated protein kinase 2 isoform X1

    Related
    ENSGALP00010003890.1, ENSGALT00010006282.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    96681924..96776486 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040668854.2 → XP_040524788.2  rho-associated protein kinase 2 isoform X4

  2. XM_040668853.2 → XP_040524787.2  rho-associated protein kinase 2 isoform X3

  3. XM_040668852.2 → XP_040524786.2  rho-associated protein kinase 2 isoform X2

  4. XM_040668851.2 → XP_040524785.2  rho-associated protein kinase 2 isoform X1

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials
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