CBL Cbl proto-oncogene [Gallus gallus (chicken)] - Gene

Summary

Symbol: CBLprovided by CGNC
Full Name: Cbl proto-oncogeneprovided by CGNC
Primary source: CGNC:49015
See related: Ensembl:ENSGALG00010024138
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 24

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	24	NC_052555.1 (4278671..4312994, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	24	NC_052596.1 (4238425..4272725, complement)

Chromosome 24 - NC_052555.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Identification of host protein CBL interacting with Eimeria acervulina microneme protein MIC3.
Title: Identification of host protein CBL interacting with Eimeria acervulina microneme protein MIC3.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables SH3 domain binding	IEA Inferred from Electronic Annotation more info	PubMed
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables phosphotyrosine residue binding	IEA Inferred from Electronic Annotation more info	PubMed
enables receptor tyrosine kinase binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ubiquitin protein ligase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell surface receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of epidermal growth factor-activated receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane raft	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: E3 ubiquitin-protein ligase CBL

Names: Cas-Br-M (murine) ecotropic retroviral transforming sequence; Cbl proto-oncogene, E3 ubiquitin protein ligase

NP_989539.2

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_204208.2 → NP_989539.2 E3 ubiquitin-protein ligase CBL

Status: VALIDATED

Source sequence(s)

JAENSK010000341

Related

ENSGALP00010035829.1, ENSGALT00010058864.1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052555.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

4278671..4312994 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)