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PCNA proliferating cell nuclear antigen [ Gallus gallus (chicken) ]

Gene ID: 373984, updated on 5-Mar-2024

Summary

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Official Symbol
PCNAprovided by CGNC
Official Full Name
proliferating cell nuclear antigenprovided by CGNC
Primary source
CGNC:92
See related
Ensembl:ENSGALG00010020374
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 22
Exon count:
6
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 22 NC_052553.1 (388903..392002)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 22 NC_052594.1 (402327..405426)

Chromosome 22 - NC_052553.1Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 25 Neighboring gene uncharacterized LOC107054953 Neighboring gene CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 Neighboring gene transmembrane protein 230 Neighboring gene uncharacterized LOC107054952 Neighboring gene solute carrier family 23 member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A genetic study based on PCNA-ubiquitin fusions reveals no requirement for PCNA polyubiquitylation in DNA damage tolerance. Gervai JZ, et al. DNA Repair (Amst), 2017 Jun. PMID 28458162
  2. PCNA ubiquitination and REV1 define temporally distinct mechanisms for controlling translesion synthesis in the avian cell line DT40. Edmunds CE, et al. Mol Cell, 2008 May 23. PMID 18498753
  3. A role for PCNA ubiquitination in immunoglobulin hypermutation. Arakawa H, et al. PLoS Biol, 2006 Nov. PMID 17105346, Free PMC Article
  4. Co-localization of chicken DNA topoisomerase IIalpha, but not beta, with sites of DNA replication and possible involvement of a C-terminal region of alpha through its binding to PCNA. Niimi A, et al. Chromosoma, 2001 May. PMID 11453553
  5. Differential expression of Sox2 and Sox3 in neuronal and sensory progenitors of the developing inner ear of the chick. Neves J, et al. J Comp Neurol, 2007 Aug 1. PMID 17534940

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. No requirement for PCNA polyubiquitylation to protect cells from replication-stalling DNA damage was found
    Title: A genetic study based on PCNA-ubiquitin fusions reveals no requirement for PCNA polyubiquitylation in DNA damage tolerance.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA polymerase processivity factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in leading strand elongation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mismatch repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in translesion synthesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of PCNA complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
proliferating cell nuclear antigen

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204170.3 → NP_989501.1  proliferating cell nuclear antigen

    See identical proteins and their annotated locations for NP_989501.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000331
    UniProtKB/Swiss-Prot
    Q9DEA3
    UniProtKB/TrEMBL
    A0A8V0Z778
    Related
    ENSGALP00010029104.1, ENSGALT00010049230.1
    Conserved Domains (1) summary
    TIGR00590
    Location:1 → 259
    pcna; proliferating cell nuclear antigen (pcna)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052553.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    388903..392002
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052594.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    402327..405426
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9DEA3.1 GenPept UniProtKB/Swiss-Prot:Q9DEA3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.