LIMK1 LIM domain kinase 1 [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: LIMK1provided by CGNC
Official Full Name: LIM domain kinase 1provided by CGNC
Primary source: CGNC:729
See related: Ensembl:ENSGALG00010029583
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	19	NC_052550.1 (1300241..1309255)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	19	NC_052591.1 (1030074..1039079)

Chromosome 19 - NC_052550.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in actin cytoskeleton organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of stress fiber assembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in neuron projection	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: LIM domain kinase 1

Names: LIMK-1; chLIMK1

NP_989462.1

EC 2.7.11.1

XP_015151143.2

EC 2.7.11.1

XP_046785826.1

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_204131.2 → NP_989462.1 LIM domain kinase 1

See identical proteins and their annotated locations for NP_989462.1

Status: PROVISIONAL

Source sequence(s)

JAENSK010000323

UniProtKB/Swiss-Prot

Q8QFP8

UniProtKB/TrEMBL

A0A8V1AMT3

Related

ENSGALP00010044200.1, ENSGALT00010071510.1

Conserved Domains (5) summary

cd09462
Location:5 → 78

LIM1_LIMK1; The first LIM domain of LIMK1 (LIM domain Kinase 1)

cd09464
Location:85 → 139

LIM2_LIMK1; The second LIM domain of LIMK1 (LIM domain Kinase 1)

smart00219
Location:349 → 611

TyrKc; Tyrosine kinase, catalytic domain

cd14221
Location:352 → 618

STKc_LIMK1; Catalytic domain of the Serine/Threonine Kinase, LIM domain kinase 1

pfam00595
Location:166 → 256

PDZ; PDZ domain (Also known as DHR or GLGF)