FZD10 frizzled class receptor 10 [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: FZD10provided by CGNC
Official Full Name: frizzled class receptor 10provided by CGNC
Primary source: CGNC:48941
See related: Ensembl:ENSGALG00010023250
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: cFz-10
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	15	NC_052546.1 (3440492..3442734, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	15	NC_052587.1 (3444845..3447087, complement)

Chromosome 15 - NC_052546.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

FZD10 regulates cell proliferation and mediates Wnt1 induced neurogenesis in the developing spinal cord.
Title: FZD10 regulates cell proliferation and mediates Wnt1 induced neurogenesis in the developing spinal cord.
results identify FZD10 as a receptor for WNT1 and WNT3A in the developing chick spinal cord.
Title: Frizzled10 mediates WNT1 and WNT3A signaling in the dorsal spinal cord of the developing chick embryo.
Expressed in the dorsal neural tube and dorsal limb bud, overlapping with Wnt7a expression, and functionally interacting with Wnt7a, but not with Wnt3a
Title: Involvement of frizzled-10 in Wnt-7a signaling during chick limb development.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables Wnt receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables Wnt-protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in canonical Wnt signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in non-canonical Wnt signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: frizzled-10

Names: frizzled 10, seven transmembrane spanning receptor; frizzled family receptor 10; frizzled homolog 10; fz-10; seven transmembrane spanning receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_204098.2 → NP_989429.1 frizzled-10 precursor

See identical proteins and their annotated locations for NP_989429.1

Status: PROVISIONAL

Source sequence(s)

AF224320

UniProtKB/Swiss-Prot

Q9PWH2

Related

ENSGALP00010034424.1, ENSGALT00010056682.1

Conserved Domains (2) summary

cd07462
Location:34 → 160

CRD_FZ10; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 10 (Fz10) receptor

pfam01534
Location:222 → 539

Frizzled; Frizzled/Smoothened family membrane region

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052546.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

3440492..3442734 complement

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GenBank, FASTA, Sequence Viewer (Graphics)