bdkrb1 bradykinin receptor B1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: bdkrb1provided by ZNC
Official Full Name: bradykinin receptor B1provided by ZNC
Primary source: ZFIN:ZDB-GENE-030814-1
See related: Ensembl:ENSDARG00000020744 AllianceGenome:ZFIN:ZDB-GENE-030814-1
Gene type: protein coding
RefSeq status: INFERRED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: bdkrb2
Summary: Enables bradykinin receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in brain and eye. Human ortholog(s) of this gene implicated in end stage renal disease; hypertension; and pulmonary fibrosis. Orthologous to human BDKRB1 (bradykinin receptor B1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 17

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (2833685..2834764, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (2657299..2658378, complement)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Cloning, structural characterization and functional expression (BRADYKININ B2 RECEPTOR)
Title: Cloning, structural characterization and functional expression of a zebrafish bradykinin B2-related receptor.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables bradykinin receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables bradykinin receptor activity	IDA Inferred from Direct Assay more info	PubMed
enables bradykinin receptor activity	IEA Inferred from Electronic Annotation more info
enables bradykinin receptor activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: B1 bradykinin receptor

Names: B1 like bradykinin receptor; bradykinin receptor B2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_183073.2 → NP_898896.2 B1 bradykinin receptor

Status: INFERRED

Source sequence(s)

BX927410

UniProtKB/TrEMBL

A0A8M1PAU7, A8E7T8

Related

ENSDARP00000007507.1, ENSDART00000024027.3

Conserved Domains (1) summary

pfam00001
Location:53 → 309

7tm_1; 7 transmembrane receptor (rhodopsin family)