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Slc5a9 solute carrier family 5 member 9 [ Rattus norvegicus (Norway rat) ]

Gene ID: 366441, updated on 30-Mar-2024

Summary

Official Symbol
Slc5a9provided by RGD
Official Full Name
solute carrier family 5 member 9provided by RGD
Primary source
RGD:1311383
See related
Ensembl:ENSRNOG00000042950 AllianceGenome:RGD:1311383
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable glucose:sodium symporter activity. Predicted to be involved in sodium ion transport. Predicted to be active in plasma membrane. Predicted to be integral component of membrane. Orthologous to human SLC5A9 (solute carrier family 5 member 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 62.4) See more
Orthologs
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Genomic context

Location:
5q35
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (131937368..131966405, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (126709762..126733468, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (131836927..131865218, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene AGBL carboxypeptidase 4 Neighboring gene BEN domain containing 5 Neighboring gene spermatogenesis associated 6 Neighboring gene selection and upkeep of intraepithelial T cells 8 Neighboring gene selection and upkeep of intraepithelial T cells 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables glucose:sodium symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in glucose transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
sodium/glucose cotransporter 4
Names
solute carrier family 5 (sodium/glucose cotransporter), member 9
solute carrier family 5 (sodium/sugar cotransporter), member 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001395128.1NP_001382057.1  sodium/glucose cotransporter 4

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    A0A0G2JY02
    Related
    ENSRNOP00000070467.2, ENSRNOT00000080242.2
    Conserved Domains (1) summary
    cl00456
    Location:48688
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    131937368..131966405 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063288113.1XP_063144183.1  sodium/glucose cotransporter 4 isoform X1

  2. XM_063288114.1XP_063144184.1  sodium/glucose cotransporter 4 isoform X2

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001108974.1: Suppressed sequence

    Description
    NM_001108974.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.