pea peanuts [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: peaprovided by FlyBase
Official Full Name: peanutsprovided by FlyBase
Primary source: FLYBASE:FBgn0086895
Locus tag: Dmel_CG8241
See related: AllianceGenome:FB:FBgn0086895
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: cg8241; CG8241; Dmel\CG8241; prp22; Prp22
Summary: Predicted to enable RNA binding activity and RNA helicase activity. Involved in chromatin organization and oogenesis. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Orthologous to human DHX8 (DEAH-box helicase 8). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (14153153..14157106)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (10040658..10044611)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Prp22 and spliceosome components regulate chromatin dynamics in germ-line polyploid cells.
Title: Prp22 and spliceosome components regulate chromatin dynamics in germ-line polyploid cells.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA helicase activity	IBA Inferred from Biological aspect of Ancestor more info
enables RNA helicase activity	IEA Inferred from Electronic Annotation more info
enables RNA helicase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in chromatin organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mRNA splicing, via spliceosome	IC Inferred by Curator more info	PubMed
involved_in mRNA splicing, via spliceosome	IEA Inferred from Electronic Annotation more info
involved_in mRNA splicing, via spliceosome	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in oogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of alternative mRNA splicing, via spliceosome	HMP more info	PubMed
involved_in spliceosomal complex disassembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in ventral cord development	HMP more info	PubMed

Component	Evidence Code	Pubs
part_of catalytic step 2 spliceosome	HDA more info	PubMed
part_of catalytic step 2 spliceosome	IBA Inferred from Biological aspect of Ancestor more info
is_active_in intracellular anatomical structure	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IC Inferred by Curator more info	PubMed
part_of precatalytic spliceosome	HDA more info	PubMed
part_of spliceosomal complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed

NP_610928.1

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