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Mat1 Menage a trois 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36130, updated on 4-Apr-2024

Summary

Official Symbol
Mat1provided by FlyBase
Official Full Name
Menage a trois 1provided by FlyBase
Primary source
FLYBASE:FBgn0024956
Locus tag
Dmel_CG7614
See related
AllianceGenome:FB:FBgn0024956
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
AT-1; CG7614; Dmel\CG7614; MAT1
Summary
Predicted to enable zinc ion binding activity. Involved in regulation of cyclin-dependent protein serine/threonine kinase activity. Part of transcription factor TFIIH holo complex. Is expressed in organism. Orthologous to human MNAT1 (MNAT1 component of CDK activating kinase). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See Mat1 in Genome Data Viewer
Location:
47B9-47B9; 2-63 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10738617..10739829, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (6626122..6627334, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Rab3 Neighboring gene Carbonic anhydrase 13 Neighboring gene D-amino acid oxidase 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43605 Neighboring gene long non-coding RNA:CR44299

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
menage a trois 1
Names
CG7614-PA
Mat1-PA
menage a trois 1 ortholog

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    10738617..10739829 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136761.3NP_610605.1  menage a trois 1 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610605.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7KPG8, Q8SX08
    Related
    FBpp0087350
    Conserved Domains (4) summary
    TIGR00570
    Location:1313
    cdk7; CDK-activating kinase assembly factor MAT1
    cl03951
    Location:66175
    CDC37_N; Cdc37 N terminal kinase binding
    cl12057
    Location:127215
    Seryl_tRNA_N; Seryl-tRNA synthetase N-terminal domain
    cl17238
    Location:347
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...