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LSm7 Like Sm 7 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35003, updated on 10-May-2024

Summary

Official Symbol
LSm7provided by FlyBase
Official Full Name
Like Sm 7provided by FlyBase
Primary source
FLYBASE:FBgn0261068
Locus tag
Dmel_CG13277
See related
AllianceGenome:FB:FBgn0261068
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RH73529; CG13277; Dmel\CG13277; Lsm7; LSM7
Summary
Predicted to contribute to RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Is expressed in embryonic brain; embryonic/larval midgut; embryonic/larval muscle system; and organism. Orthologous to human LSM7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
36A14-36A14; 2-52 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (16742315..16743100, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (16742315..16743100, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Proteasome beta4 subunit Neighboring gene tRNA splicing endonuclease subunit 2 Neighboring gene NUBP iron-sulfur cluster assembly factor 1 Neighboring gene gluon Neighboring gene Chitin and LDLR binding deacetylase 3 Neighboring gene Bub3 interacting GLEBS and Zinc finger domain protein Neighboring gene yellow-b Neighboring gene pickpocket 17

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
contributes_to RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IC
Inferred by Curator
more info
PubMed 
involved_in mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 
involved_in mRNA splicing, via spliceosome ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in nuclear-transcribed mRNA catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of Lsm1-7-Pat1 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U12-type spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U2-type prespliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U6 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U6 snRNP ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
part_of catalytic step 2 spliceosome HDA PubMed 
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of precatalytic spliceosome HDA PubMed 
part_of spliceosomal tri-snRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
uncharacterized protein
NP_001246045.1
  • like Sm 7, isoform B
NP_001285985.1
  • like Sm 7, isoform C
NP_609807.1
  • like Sm 7, isoform A

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    16742315..16743100 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299056.1NP_001285985.1  uncharacterized protein Dmel_CG13277 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285985.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B1PFP9, Q9VJI7
    Conserved Domains (1) summary
    cd01729
    Location:18107
    LSm7; Like-Sm protein 7
  2. NM_135963.4NP_609807.1  uncharacterized protein Dmel_CG13277 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609807.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B1PFP9, Q9VJI7
    Related
    FBpp0080488
    Conserved Domains (1) summary
    cd01729
    Location:18107
    LSm7; Like-Sm protein 7
  3. NM_001259116.3NP_001246045.1  uncharacterized protein Dmel_CG13277 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246045.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B1PFP9, Q9VJI7
    Conserved Domains (1) summary
    cd01729
    Location:18107
    LSm7; Like-Sm protein 7