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Rnmt RNA guanine-7 methyltransferase [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34877, updated on 10-May-2024

Summary

Official Symbol
Rnmtprovided by FlyBase
Official Full Name
RNA guanine-7 methyltransferaseprovided by FlyBase
Primary source
FLYBASE:FBgn0286027
Locus tag
Dmel_CG3688
See related
AllianceGenome:FB:FBgn0286027
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BG:DS00929.5; br9; C2; CG3688; Dmel\CG3688; l(2)10408; l(2)35Bd; l(2)br9; RNA-guanine-7-methyltransferase
Summary
Predicted to enable RNA binding activity and mRNA (guanine-N7-)-methyltransferase activity. Predicted to be involved in 7-methylguanosine mRNA capping. Predicted to be part of mRNA cap binding activity complex. Predicted to be active in nucleus. Is expressed in embryonic/larval brain and gonad. Orthologous to human RNMT (RNA guanine-7 methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
35B8-35B8; 2-50 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (15009939..15011764)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (15009939..15011764)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Dynactin 5, p25 subunit Neighboring gene Ankrd49 Neighboring gene Negative Cofactor 2beta Neighboring gene long non-coding RNA:CR43856 Neighboring gene tRNA-histidine guanylyltransferase Neighboring gene metabotropic GABA-B receptor subtype 1 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables mRNA 5'-cap (guanine-N7-)-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables mRNA 5'-cap (guanine-N7-)-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables mRNA 5'-cap (guanine-N7-)-methyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in 7-methylguanosine mRNA capping IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in 7-methylguanosine mRNA capping IEA
Inferred from Electronic Annotation
more info
 
involved_in 7-methylguanosine mRNA capping ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
RNA guanine-7 methyltransferase
Names
CG3688-PA
RNA (guanine-7-)methyltransferase
Rnmt-PA
lethal (2) 35Bd
lethal 9 in the black-reduced region
lethal group C2
NP_523568.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    15009939..15011764
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078844.4NP_523568.2  RNA guanine-7 methyltransferase [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523568.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9N6X4, Q9VJQ4
    Related
    FBpp0080257
    Conserved Domains (1) summary
    pfam03291
    Location:72411
    Pox_MCEL; mRNA capping enzyme