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eEF1delta eukaryotic translation elongation factor 1 delta [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34363, updated on 5-May-2024

Summary

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Official Symbol
eEF1deltaprovided by FlyBase
Official Full Name
eukaryotic translation elongation factor 1 deltaprovided by FlyBase
Primary source
FLYBASE:FBgn0032198
Locus tag
Dmel_CG4912
See related
AllianceGenome:FB:FBgn0032198
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG4912; Dmel\CG4912; eEF1d; eEf1delta
Summary
Predicted to enable guanyl-nucleotide exchange factor activity and translation elongation factor activity. Predicted to be involved in translational elongation. Predicted to be part of eukaryotic translation elongation factor 1 complex. Predicted to be active in cytosol. Is expressed in several structures, including anterior endoderm; embryonic/larval muscle system; extended germ band embryo; foregut primordium; and gut section. Orthologous to human EEF1D (eukaryotic translation elongation factor 1 delta). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
31B1-31B1; 2-40 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10232507..10234450)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10232507..10234450)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ovaries absent Neighboring gene methuselah-like 15 Neighboring gene maternal expression at 31B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Global analysis of positive and negative pre-mRNA splicing regulators in Drosophila. Blanchette M, et al. Genes Dev, 2005 Jun 1. PMID 15937219, Free PMC Article
  2. Enhancer-core-promoter specificity separates developmental and housekeeping gene regulation. Zabidi MA, et al. Nature, 2015 Feb 26. PMID 25517091, Free PMC Article
  3. A Quantitative Proteomic Analysis of In Vitro Assembled Chromatin. Völker-Albert MC, et al. Mol Cell Proteomics, 2016 Mar. PMID 26811354, Free PMC Article
  4. Genome-wide assessment of AU-rich elements by the AREScore algorithm. Spasic M, et al. PLoS Genet, 2012 Jan. PMID 22242014, Free PMC Article
  5. Extensive use of RNA-binding proteins in Drosophila sensory neuron dendrite morphogenesis. Olesnicky EC, et al. G3 (Bethesda), 2014 Feb 19. PMID 24347626, Free PMC Article

See all (45) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables translation elongation factor activity IEA
Inferred from Electronic Annotation
more info
  
enables translation elongation factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in translational elongation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translational elongation IEA
Inferred from Electronic Annotation
more info
  
involved_in translational elongation ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of eukaryotic translation elongation factor 1 complex IEA
Inferred from Electronic Annotation
more info
  
part_of eukaryotic translation elongation factor 1 complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
eukaryotic translation elongation factor 1 delta
Names
CG4912-PA
CG4912-PB
eEF1delta-PA
eEF1delta-PB
eukaryotic translation elongation factor 1delta

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    10232507..10234450
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135517.4 → NP_609361.1  eukaryotic translation elongation factor 1 delta, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609361.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VL18, Q9VL19
    Related
    FBpp0079542
    Conserved Domains (2) summary
    cd00292
    Location:168 → 256
    EF1B; Elongation factor 1 beta (EF1B) guanine nucleotide exchange domain. EF1B catalyzes the exchange of GDP bound to the G-protein, EF1A, for GTP, an important step in the elongation cycle of the protein biosynthesis. EF1A binds to and delivers the aminoacyl ...
    pfam10587
    Location:134 → 156
    EF-1_beta_acid; Eukaryotic elongation factor 1 beta central acidic region

  2. NM_164895.3 → NP_723536.1  eukaryotic translation elongation factor 1 delta, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723536.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VL18
    Related
    FBpp0079541
    Conserved Domains (2) summary
    cd00292
    Location:141 → 229
    EF1B; Elongation factor 1 beta (EF1B) guanine nucleotide exchange domain. EF1B catalyzes the exchange of GDP bound to the G-protein, EF1A, for GTP, an important step in the elongation cycle of the protein biosynthesis. EF1A binds to and delivers the aminoacyl ...
    pfam10587
    Location:107 → 129
    EF-1_beta_acid; Eukaryotic elongation factor 1 beta central acidic region
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VL18.1 Q9VL18

Gene LinkOut

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