x16 x16 splicing factor [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: x16provided by FlyBase
Official Full Name: x16 splicing factorprovided by FlyBase
Primary source: FLYBASE:FBgn0028554
Locus tag: Dmel_CG10203
See related: AllianceGenome:FB:FBgn0028554
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 2/30; 9G8; anon-WO0118547.78; CG10203; d9G8; Dmel\CG10203; dx16; Dx16; dxl6; Dxl6; l(2)k00230; RBP1-like; TN166; X16; X16/9G8; xl6; Xl6; XL6
Summary: Enables mRNA binding activity. Involved in RNA splicing and regulation of RNA metabolic process. Located in nucleus. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Is expressed in several structures, including ectoderm; embryonic/larval nervous system; extended germ band embryo; imaginal disc; and presumptive embryonic/larval central nervous system. Orthologous to several human genes including SRSF7 (serine and arginine rich splicing factor 7). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (6914301..6920210, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (6914301..6920210, complement)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables RNA binding	ISM Inferred from Sequence Model more info	PubMed
enables mRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables mRNA binding	IDA Inferred from Direct Assay more info	PubMed
enables mRNA binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in RNA splicing	IPI Inferred from Physical Interaction more info	PubMed
involved_in mRNA splicing, via spliceosome	IBA Inferred from Biological aspect of Ancestor more info
involved_in mRNA splicing, via spliceosome	IC Inferred by Curator more info	PubMed
involved_in mRNA splicing, via spliceosome	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in regulation of alternative mRNA splicing, via spliceosome	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of gene expression	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of mRNA 3'-end processing	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of transcriptional start site selection at RNA polymerase II promoter	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of catalytic step 2 spliceosome	HDA more info	PubMed
is_active_in nuclear speck	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
part_of precatalytic spliceosome	HDA more info	PubMed

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