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rps12 ribosomal protein S12 [ Danio rerio (zebrafish) ]

Gene ID: 337007, updated on 27-Mar-2024

Summary

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Official Symbol
rps12provided by ZNC
Official Full Name
ribosomal protein S12provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-8951
See related
Ensembl:ENSDARG00000036875 AllianceGenome:ZFIN:ZDB-GENE-030131-8951
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fa95a02; zgc:73055; wu:fa95a02
Summary
Predicted to be a structural constituent of ribosome. Predicted to act upstream of or within translation. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Orthologous to human RPS12 (ribosomal protein S12). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See rps12 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (31431956..31435923)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (31505425..31509392)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene si:dkeyp-79f12.7 Neighboring gene SH3 domain binding glutamate-rich protein like 2 Neighboring gene zgc:153284 Neighboring gene EYA transcriptional coactivator and phosphatase 4 Neighboring gene transcription factor 21

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Systematic identification of seven ribosomal protein genes in bighead carp and their expression in response to microcystin-LR. Cai Y, et al. J Toxicol Sci, 2016 Apr. PMID 26961614
  2. Many ribosomal protein genes are cancer genes in zebrafish. Amsterdam A, et al. PLoS Biol, 2004 May. PMID 15138505, Free PMC Article
  3. Oocyte-specific maternal Slbp2 is required for replication-dependent histone storage and early nuclear cleavage in zebrafish oogenesis and embryogenesis. He WX, et al. RNA, 2018 Dec. PMID 30185624, Free PMC Article
  4. An environmentally relevant mixture of polychlorinated biphenyls (PCBs) and polybrominated diphenylethers (PBDEs) disrupts mitochondrial function, lipid metabolism and neurotransmission in the brain of exposed zebrafish and their unexposed F2 offspring. Blanc M, et al. Sci Total Environ, 2021 Feb 1. PMID 32911150
  5. GLUT12 deficiency during early development results in heart failure and a diabetic phenotype in zebrafish. Jiménez-Amilburu V, et al. J Endocrinol, 2015 Jan. PMID 25326603

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in maintenance of translational fidelity IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal small subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
40S ribosomal protein S12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001282177.1 → NP_001269106.1  40S ribosomal protein S12

    See identical proteins and their annotated locations for NP_001269106.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    BI326372, CT698501
    UniProtKB/TrEMBL
    F6NJU2, F6NXQ3, Q6PC90
    Related
    ENSDARP00000120403.1, ENSDART00000138350.3
    Conserved Domains (1) summary
    pfam01248
    Location:16 → 111
    Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

  2. NM_200046.3 → NP_956340.1  40S ribosomal protein S12

    See identical proteins and their annotated locations for NP_956340.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    BI326372, CR759830
    UniProtKB/TrEMBL
    F6NJU2, F6NXQ3, Q6PC90
    Related
    ENSDARP00000053541.5, ENSDART00000053542.6
    Conserved Domains (1) summary
    pfam01248
    Location:16 → 111
    Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    31431956..31435923
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395159.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    272500..276432
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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