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rps3 ribosomal protein S3 [ Danio rerio (zebrafish) ]

Gene ID: 336550, updated on 11-Apr-2024

Summary

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Official Symbol
rps3provided by ZNC
Official Full Name
ribosomal protein S3provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-8494
See related
Ensembl:ENSDARG00000103007 AllianceGenome:ZFIN:ZDB-GENE-030131-8494
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb13d09; zgc:56088; wu:fb13d09
Summary
Predicted to be a structural constituent of ribosome. Acts upstream of or within chordate embryonic development and erythrocyte differentiation. Predicted to be located in mitochondrial inner membrane; ribosome; and spindle. Predicted to be part of cytosolic small ribosomal subunit. Predicted to be active in nucleus. Orthologous to human RPS3 (ribosomal protein S3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See rps3 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (3038173..3049799)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (3045142..3056768, complement)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene F-BAR and double SH3 domains protein 2-like Neighboring gene NACHT and WD repeat domain-containing protein 2-like Neighboring gene NACHT and WD repeat domain-containing protein 2-like Neighboring gene potassium channel tetramerization domain containing 14 Neighboring gene integrator complex subunit 4 Neighboring gene adipogenesis associated, Mth938 domain containing

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Ribosomal protein deficiency causes Tp53-independent erythropoiesis failure in zebrafish. Yadav GV, et al. Int J Biochem Cell Biol, 2014 Apr. PMID 24417973
  2. Ribosomal protein gene knockdown causes developmental defects in zebrafish. Uechi T, et al. PLoS One, 2006 Dec 20. PMID 17183665, Free PMC Article
  3. An in silico mining for simple sequence repeats from expressed sequence tags of zebrafish, medaka, Fundulus, and Xiphophorus. Ju Z, et al. In Silico Biol, 2005. PMID 16268789
  4. Anti-apoptotic effects of IGF-I on mortality and dysmorphogenesis in tbx5-deficient zebrafish embryos. Tsai TC, et al. BMC Dev Biol, 2018 Mar 5. PMID 29506474, Free PMC Article
  5. Expression of Protein-Coding Gene Orthologs in Zebrafish and Mouse Inner Ear Non-sensory Supporting Cells. Giffen KP, et al. Front Neurosci, 2019. PMID 31680844, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC56088

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables class I DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
Inferred from Electronic Annotation
more info
  
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within DNA repair IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within apoptotic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within chordate embryonic development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within erythrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of apoptotic signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of translation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  
part_of small ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
located_in spindle IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
40S ribosomal protein S3
NP_957447.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201153.1 → NP_957447.1  40S ribosomal protein S3

    See identical proteins and their annotated locations for NP_957447.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045902
    UniProtKB/TrEMBL
    Q7ZVD9
    Related
    ENSDARP00000132180.1, ENSDART00000162657.2
    Conserved Domains (3) summary
    cd02413
    Location:15 → 95
    40S_S3_KH; K homology RNA-binding (KH) domain of the eukaryotic 40S small ribosomal subunit protein S3. S3 is part of the head region of the 40S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel. The KH ...
    PTZ00084
    Location:4 → 216
    PTZ00084; 40S ribosomal protein S3; Provisional
    pfam00189
    Location:105 → 186
    Ribosomal_S3_C; Ribosomal protein S3, C-terminal domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    3038173..3049799
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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