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Dim1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33645, updated on 10-May-2024

Summary

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Official Symbol
Dim1provided by FlyBase
Primary source
FLYBASE:FBgn0031601
Locus tag
Dmel_CG3058
See related
AllianceGenome:FB:FBgn0031601
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RE13747; CG3058; Dmel\CG3058; U5-15kD
Summary
Predicted to be involved in mRNA splicing, via spliceosome. Part of precatalytic spliceosome. Is expressed in organism. Human ortholog(s) of this gene implicated in Burn-McKeown syndrome. Orthologous to human TXNL4A (thioredoxin like 4A). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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Location:
24F1-24F1; 2-12 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4403251..4403955)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4403251..4403955)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene lethal (2) k05819 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene transfer RNA:Tryptophan-CCA 2-1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression of human PQBP-1 in Drosophila impairs long-term memory and induces abnormal courtship. Yoshimura N, et al. FEBS Lett, 2006 Apr 17. PMID 16597440
  2. The splicing co-factor Barricade/Tat-SF1 is required for cell cycle and lineage progression in Drosophila neural stem cells. Abramczuk MK, et al. Development, 2017 Nov 1. PMID 28935704
  3. The Output of Protein-Coding Genes Shifts to Circular RNAs When the Pre-mRNA Processing Machinery Is Limiting. Liang D, et al. Mol Cell, 2017 Dec 7. PMID 29174924, Free PMC Article
  4. A functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in Drosophila. Ashton-Beaucage D, et al. PLoS Biol, 2014 Mar. PMID 24643257, Free PMC Article
  5. Cross-species identification of PIP5K1-, splicing- and ubiquitin-related pathways as potential targets for RB1-deficient cells. Parkhitko AA, et al. PLoS Genet, 2021 Feb. PMID 33591981, Free PMC Article

See all (38) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IC
Inferred by Curator
more info
 PubMed 
involved_in mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
  
involved_in mRNA splicing, via spliceosome ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
part_of U4/U6 x U5 tri-snRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U4/U6 x U5 tri-snRNP complex IEA
Inferred from Electronic Annotation
more info
  
part_of U5 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of precatalytic spliceosome HDA PubMed 
part_of small nuclear ribonucleoprotein complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
part_of spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Dim1
Names
CG3058-PA
Dim1-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    4403251..4403955
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_134986.3 → NP_608830.3  Dim1 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608830.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SZ87, Q9VQZ2
    Related
    FBpp0077125
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SZ87 Q8SZ87

Gene LinkOut

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