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RpL40 Ribosomal protein L40 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33629, updated on 4-Apr-2024

Summary

Official Symbol
RpL40provided by FlyBase
Official Full Name
Ribosomal protein L40provided by FlyBase
Primary source
FLYBASE:FBgn0003941
Locus tag
Dmel_CG2960
See related
AllianceGenome:FB:FBgn0003941
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RE10554; CEP52; CG2960; Dmel\CG2960; Dub52; DUb52; L40; L40e; Rpl40; RPL40; Ub52; Ubi-f; Ubi-f52; Ubiq
Summary
Predicted to enable protein tag and ubiquitin protein ligase binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Part of cytosolic large ribosomal subunit. Is expressed in several structures, including Malpighian tubule; adult heart; embryonic/larval digestive system; embryonic/larval fat body; and gonad. Orthologous to human UBA52 (ubiquitin A-52 residue ribosomal protein fusion product 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:
24E1-24E1; 2-12 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4227699..4228561)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4227699..4228561)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene fat Neighboring gene long non-coding RNA:CR44608 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45720

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables protein tag activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein tag activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of ribosome TAS
Traceable Author Statement
more info
PubMed 
enables ubiquitin protein ligase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in cytoplasmic translation TAS
Traceable Author Statement
more info
PubMed 
involved_in modification-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein modification process ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein ubiquitination ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
involved_in translation TAS
Traceable Author Statement
more info
PubMed 
involved_in ubiquitin-dependent protein catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
PubMed 
part_of cytosolic large ribosomal subunit TAS
Traceable Author Statement
more info
PubMed 
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ribosomal protein L40
Names
CG2960-PA
CG2960-PB
RpL40-PA
RpL40-PB
ubiquitin
ubiquitin 52-AA extension protein
ubiquitin fusion 52

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    4227699..4228561
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273089.2NP_001260018.1  ribosomal protein L40, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260018.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P18101, P68198, Q0E8I1, Q9VKW6, Q9VQX7, Q9VZL4
    UniProtKB/TrEMBL
    Q7JYK1
    Conserved Domains (2) summary
    cd01803
    Location:176
    Ubl_ubiquitin; ubiquitin-like (Ubl) domain found in ubiquitin
    pfam01020
    Location:79126
    Ribosomal_L40e; Ribosomal L40e family
  2. NM_057428.4NP_476776.1  ribosomal protein L40, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_476776.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P18101, P68198, Q0E8I1, Q9VKW6, Q9VQX7, Q9VZL4
    UniProtKB/TrEMBL
    Q7JYK1
    Related
    FBpp0077159
    Conserved Domains (2) summary
    cd01803
    Location:176
    Ubl_ubiquitin; ubiquitin-like (Ubl) domain found in ubiquitin
    pfam01020
    Location:79126
    Ribosomal_L40e; Ribosomal L40e family