eci1 enoyl-CoA delta isomerase 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: eci1provided by ZNC
Official Full Name: enoyl-CoA delta isomerase 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-6033
See related: Ensembl:ENSDARG00000018002 AllianceGenome:ZFIN:ZDB-GENE-030131-6033
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: dci; wu:fi31d10
Summary: Predicted to enable enoyl-CoA hydratase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be active in mitochondrion. Orthologous to human ECI1 (enoyl-CoA delta isomerase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (27770110..27777671)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (27639268..27646829)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb05f03.x1 (e-PCR)
- UniSTS:189902

AW175027 (e-PCR)
- UniSTS:205785

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables delta(3)-delta(2)-enoyl-CoA isomerase activity	IBA Inferred from Biological aspect of Ancestor more info
enables delta(3)-delta(2)-enoyl-CoA isomerase activity	IEA Inferred from Electronic Annotation more info
enables isomerase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in fatty acid beta-oxidation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: enoyl-CoA delta isomerase 1, mitochondrial

Names: dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase)

NP_001292513.1

EC 5.3.3.8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001305584.1 → NP_001292513.1 enoyl-CoA delta isomerase 1, mitochondrial

Status: VALIDATED

Source sequence(s)

BX936335, EH478593, EH485677, EH580202

UniProtKB/TrEMBL

A0A8M1P1C1

Related

ENSDARP00000002223.8, ENSDART00000017962.10

Conserved Domains (1) summary

cl23717
Location:53 → 297

crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...